IgG4 related Inflammatory Pancreatic Head Pseudotumor Mirror Pancreatic Carcinoma: A Novel Case Series with a Review of the Literature

Khan, Faheemullah; Shahid, Jehanzeb; Saleem, Amna; Khawaja, Uzzam Ahmed; Memon, Wasim; Zafar, Uffan; Hameed, Tariq; Ahmed, Khabab Abbasher Hussien Mohamed

doi:10.22541/au.168069251.17896424/v1

Cited by 1 publication

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“…However, in case of an autoimmune IgG4‐related pathological presentation, steroids remain as the mainstay treatment. 11 …”

Section: Discussionmentioning

confidence: 99%

Duodenal stricture secondary to IgG4‐related chronic sclerosing duodenitis—A case report with review of the literature

Anns,

Salar,

Salar

et al. 2024

Clinical Case Reports

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Key Clinical MessageThis case highlights the importance of a definite diagnosis of an IgG4‐related chronic sclerosing duodenitis based on histological and radiological findings to rule out any malignancy in the mass. While dealing with patients having concentric duodenal thickening resulting in stricture formation, one should think of inflammatory etiology as well. IgG4‐related disease is one of these inflammatory disorders where we see soft tissue thickening without a large mass or any associated lymphadenopathy as in our case.AbstractImmunoglobulin G4‐related disease (IgG4‐RD) is distinguished as an infiltration of IgG‐4‐positive plasmacytes involving inflammatory lesions across multiple organs which is accompanied by raised IgG4 levels in the serum. Several inflammatory disorders are recognized as part of the IgG4‐RD family based on shared histopathological features, which include Mikulicz's disease, chronic sclerosing sialadenitis, or Riedel's thyroiditis. Our case highlights a distinctive presentation of IgG4‐related diseases; a 58‐year‐old man presenting with duodenal stricture highly suspicious of a duodenal mass/ampullary mass later found to be due to IgG4‐related sclerosing duodenitis with negative malignancy on biopsy. We present the diagnostic challenges faced and relevant findings noted.

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“…However, in case of an autoimmune IgG4‐related pathological presentation, steroids remain as the mainstay treatment. 11 …”

Section: Discussionmentioning

confidence: 99%

Duodenal stricture secondary to IgG4‐related chronic sclerosing duodenitis—A case report with review of the literature

Anns,

Salar,

Salar

et al. 2024

Clinical Case Reports

Self Cite

View full text Add to dashboard Cite

show abstract

IgG4 related Inflammatory Pancreatic Head Pseudotumor Mirror Pancreatic Carcinoma: A Novel Case Series with a Review of the Literature

Abstract: This a preprint and has not been peer reviewed. Data may be preliminary.

Cited by 1 publication

References 22 publications

Duodenal stricture secondary to IgG4‐related chronic sclerosing duodenitis—A case report with review of the literature

Duodenal stricture secondary to IgG4‐related chronic sclerosing duodenitis—A case report with review of the literature

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