IGG Antibodies to Beta-Lactoglobulin and Cow's Milk Protein Intolerance in Down Syndrome

Failla, Pinella; Barone, C. N.; Pettinato, Rosa; Romano, Corrado

doi:10.3104/reports.86

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…Symptoms of gastro-oesophageal reflux can be managed with H2-receptor antagonists. 15 Obstructive sleep apnea was seen in three of our patients (10%). OSA can affect up to 50% of the paediatric DS population, with >90% of DS adults manifesting some aspect of OSA.…”

Section: Discussionmentioning

confidence: 62%

Otorhinolaryngological manifestations in Down syndrome: MERF experience

Anto¹,

Natarajan²,

Sampathkumar³

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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Background: Syndromic children often pose a spectrum of challenges to the paediatric otolaryngologist. Syndromes like the Down syndrome present with a multitude of manifestations in the head and neck region and require careful management.Methods: A retrospective study of thirty patients with Down syndrome presenting from January 2013 to January 2018 in a tertiary care setting was done. All patients were evaluated by ENT examination and further investigations based on the complaints. The aim was to study the various ENT disorders in Down syndrome patients and their management. Results: The most common disorder was hearing loss in eleven patients followed by rhinosinusitis in ten patients, adenoid hypertrophy and otitis media with effusion (OME) in six patients and obstructive sleep apnea in three patients. Most of the patients had medical management; very few needed surgery. Successful outcomes were possible for all patients.Conclusions: Dealing with otorhinolaryngological disorders may pose a management challenge in Down syndrome and this requires a well experienced ENT, medical and rehabilitative team to provide optimal management and good quality of life to these children.

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Section: Discussionmentioning

confidence: 62%

Otorhinolaryngological manifestations in Down syndrome: MERF experience

Anto¹,

Natarajan²,

Sampathkumar³

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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show abstract

“…Adenoidectomy has a role for some children but the results for rhinorrhoea are disappointing. Bear in mind that children with Down’s syndrome also have a higher incidence of intolerance to dairy products 22 and laryngopharyngeal reflux, which can contribute to nasal and throat symptoms. Symptoms of gastro‐oesophageal reflux can be managed with infant gaviscon and or H2‐receptor antagonists that can be added to feeds.…”

Section: What Management Should You Offer?mentioning

confidence: 99%

“…Down's syndrome affects 1 : 1000 children born 1 and is the commonest genetic abnormality. These children have cognitive impairment that is variable and can be mild (IQ of 50-70), moderate (IQ of 35-50) or occasionally severe (IQ of [20][21][22][23][24][25][26][27][28][29][30]. The degree of cooperation with the child varies with the severity of learning difficulties.…”

mentioning

confidence: 99%

An evidence‐based approach to the 12‐min consultation for a child with Down’s syndrome

Malik¹,

Verma²,

Joshi³

et al. 2012

Clinical Otolaryngology

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An overview and update regarding medical problems in down syndrome

Grech

2001

Indian J Pediatr

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Down syndrome is the commonest occurring syndrome, and because of the high risk of congenital heart disease, these children are frequently seen at cardiology clinics and wards. However, these individuals are also likely to have a variety of other-problems, both congenital and acquired, which may impinge on the medical and surgical management of cardiac problems. It is therefore important for the paediatric cardiology community to maintain a minimum level of expertise in other noncardiac aspects of the syndrome. This paper reviews Down syndrome, lists congenital and acquire disorders that may occur, and briefly addresses recent advances in the understanding of this condition.

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IGG Antibodies to Beta-Lactoglobulin and Cow's Milk Protein Intolerance in Down Syndrome

Cited by 4 publications

References 11 publications

Otorhinolaryngological manifestations in Down syndrome: MERF experience

Otorhinolaryngological manifestations in Down syndrome: MERF experience

An evidence‐based approach to the 12‐min consultation for a child with Down’s syndrome

An overview and update regarding medical problems in down syndrome

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