IgE Levels in Nummular Eczema and Ichthyosis

Krueger, Gerald G.

doi:10.1001/archderm.1973.01620160028006

Cited by 29 publications

(6 citation statements)

References 10 publications

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“…The pathogenesis of discoid eczema is not known. Unlike atopic eczema, there does not appear to be a clear association with atopy 1,2 . Although xerosis has been reported in patients with discoid eczema, dry skin is not present in all patients 3 .…”

Section: Introductionmentioning

confidence: 88%

Methotrexate is a safe and effective treatment for paediatric discoid (nummular) eczema: A case series of 25 children

Roberts

Orchard

2010

Aust J Dermatology

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We present a case series of 25 paediatric patients with refractory discoid eczema treated with methotrexate. Patients were commenced on either 5 mg or 10 mg of methotrexate per week. Sixteen patients (64%) completely cleared their eczema after an average of 10.5 months of methotrexate therapy. A further three patients (12%) have responded well and are almost clear at the time of writing. Methotrexate was well tolerated by the majority of patients and no serious adverse events were observed. Methotrexate should be considered in moderate to severe paediatric discoid eczema that has failed to respond to conventional therapies.

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Section: Introductionmentioning

confidence: 88%

Methotrexate is a safe and effective treatment for paediatric discoid (nummular) eczema: A case series of 25 children

Roberts

Orchard

2010

Aust J Dermatology

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“…The majority of studies evidence no association between discoid eczema and atopy, 3,4,35,36 partly based on the observation of lower immunoglobulin E serum levels in the former than in the latter. 37 Nevertheless, atopic dermatitis can manifest with nummular lesions, albeit generally not very exudative and usually just scaly, both in children and adults, with a respective incidence of 9% and 12%. 38…”

Section: Clinical Considerationsmentioning

confidence: 99%

Nummular Eczema and Contact Allergy

Bonamonte¹,

Foti²,

Vestita³

et al. 2012

Dermatitis

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“…The extent of involvement may range from a few lesions to numerous plaques, usually located on the extensor aspect of the extremities and the trunk . Nummular eczema often occurs independent of atopic dermatits (AD), and overall, there is no higher incidence of atopy in patients with NE, although NE lesions have been reported to occur in children with AD . The “dry,” discoid eczema lesions that usually appear in children with AD should not be confused with NE (Figure ).…”

Section: Introductionmentioning

confidence: 99%