Abstract:Background and Purpose Neutrophils and the release of neutrophil
extracellular traps (NETs) play important roles in the pathogenesis of
RA. However, IgD, which was abnormally higher in RA, has not been
studied for its pathological role in neutrophil activation and NETs
formation. Experimental Approach Peripheral blood of RA patients and
healthy controls were collected and adjuvant-induced arthritis (AA) rat
models were established. Body weights, the severity of arthritis of AA
rats were monitored regularly. Af… Show more
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