IgA Vasculitis in the Setting of Biologic Therapy for Psoriasis and Recurrent Cutaneous Methicillin-Resistant Staphylococcus aureus Colonization

Young, Iain M.

doi:10.12788/cutis.0636

Cited by 1 publication

(1 citation statement)

References 13 publications

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“…Regarding treatment, the effectiveness of corticosteroids in the prevention of severe complications and recurrence is controversial as they may mask the complications of abdominal surgery, such as fever and abdominal pain. [21][22][23] Moreover, the use of glucocorticoids may impair the healing of the incision; therefore, it is necessary to decide between creating a fistula or an anastomosis to avoid postoperative complications. We found that 24 early application of glucocorticoids in the treatment of HSP with gastrointestinal involvement is beneficial to the prevention of intussusception.…”

Section: Treatmentmentioning

confidence: 99%

Immunoglobulin A Vasculitis With Intussusception in Children

Liu,

Du,

Zhao

et al. 2024

The American Surgeon™

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Background Immunoglobulin A (IgA) vasculitis with intussusception is acute and severe vasculitis combined with acute abdomen in children. The diagnosis of the disease depends on the results of imaging examinations, and its treatment mainly includes enema and surgery. The literature summarized the detailed diagnosis and treatment data in previous literature reports. Methods We described the clinical manifestations, ultrasonic features, and treatment of patients admitted to a single center and reviewed previous literature regarding cases with detailed clinical data in the PubMed database within the past 20 years. Results The review included 36 patients, including 22 boys and 14 girls. A total of 32 patients were diagnosed using ultrasound (88.9%). The main sites of intussusception were the ileum and ileocolon in 16 (44.4%) and 11 (30.6%) cases, respectively. Thirteen patients (36.1%) were treated with enema, with 6 responding to the treatment. 26 patients (72.2%) underwent surgical treatment. Patients with ileal intussusception were more likely to be treated with surgery than those with colonic intussusception ( P < .05). The single-center clinical data of 23 patients showed that there was no significant difference in laboratory test findings between patients with and without surgical treatment ( P > .05). Patients with long insertion lengths were more likely to require surgery and resection ( P < .05). Conclusions Ultrasonography is the first-line investigation for diagnosis. The main sites of intussusception were ileum and ileocolon. The length of intubation was related to surgery; treatment is according to the intussusception site. Air enema is not suitable for intussusception of the small intestine.

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