Abstract:Background: Immunosuppression and frequent infections has impact on morbidity and mortality in CLL patients. It is basic related with chronic immune dysregulation or treatment toxicities. Hypogammaglobulin is a frequent event in CLL and can explain some of the infection susceptibility related to the disease. Low IgG levels were associated with a higher frequency of bacterial infections, commonly Streptococcus pneumoniae and Haemophilus influenza. Although hypogammaglobulin can contribute with repeated infectio… Show more
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