Ig heavy chain genes and their locus in grass carp Ctenopharyngodon idella

Transcriptome analysis of soiny mullet (Liza haematocheila) spleen in response to Streptococcus dysgalactiae

“…The criteria for assessing the significant DEGs was set at FDR 0.001 and the absolute value of log2ratio (fold change between uninfected/infected samples) !1. [42], and three Ig isotypes, IgM, IgD, and IgZ/T identified in fish [43]. In the present study, we identified three Ig isotypes (IgM, IgD, and IgZ) in the soiny mullet spleen transcriptome based on KEGG analysis, which enriches knowledge of soiny mullet humoral immunity.…”

Molecular cloning and functional characterization of peptidoglycan recognition protein 6 in grass carp Ctenopharyngodon idella

“…Grass carp, Ctenopharyngodon idella, one of the most popular and economically important species in aquaculture industry of China, has received increasing attention in relation to its immune system (Chen et al, 2012(Chen et al, , 2010aXu et al, 2010;Xiao et al, 2010), and a short PGRP with amidase activity (gcPGRP5) has recently been characterized in this fish (Li et al, 2013). In the present study, a long PGRP, designated as gcPGRP6 was cloned from grass carp.…”

Functional characterization of IgM+ B cells and adaptive immunity in lumpfish (Cyclopterus lumpus L.)

“…Different subsets of B cells have been reported for different species: IgM + /IgD + /IgT − , IgM − /IgD + /IgT − and IgM − /IgD − /IgT + in rainbow trout (Castro et al, 2014;Ramirez-Gomez et al, 2012;Zhang et al, 2010) and IgM + /IgD − , IgM + /IgD + and IgM − /IgD + in channel catfish (Edholm et al, 2010;reviewed in Salinas et al, 2011). Most fish species have IgT orthologs, such as zebrafish (Danilova et al, 2005), rainbow trout (Hansen et al, 2005), fugu (Savan et al, 2005), carp (Ryo et al, 2010;Savan et al, 2005;Xiao et al, 2010) and salmon (Tadiso et al, 2011). To date, catfish is the only species where an IgT equivalent has not been identified.…”