Idiopathic Ventricular Arrhythmia Ablation Using Non-Fluoroscopic Catheter Visualization System

Abstract

A novel, sensor-based, electromagnetic, non-fluoroscopic catheter visualization (NFCV) system shows tracked catheters directly on pre-acquired fluoroscopy or cine loops. We aimed to evaluate the effectiveness of this system in the setting of catheter ablation for idiopathic premature ventricular contractions/ventricular tachycardia (i-PVC/VT). A total of 30 i-PVC/VT ablation procedures were performed using the NFCV system in conjunction with three-dimensional electroanatomic mapping system (3D-EMS) between January 2013 and April 2017. At the beginning of the procedure, cine loops of right and left anterior oblique views were obtained and replayed for subsequent mapping and ablation. Right ventriculography, aortography, or coronary angiography was performed, depending on the chamber of interest. We reviewed procedural parameters, comparing with the i-PVC/VT ablation procedure using conventional fluoroscopy (CvF) system (pre-, and post-NFCV implementation; 20 and 11 cases, respectively). I-PVC/VTs were successfully eliminated in 26 patients (87%) in the NFCV group and in 26 (84%) in the CvF group (P = 1.000). The procedure time in the NFCV group was comparable to that in the CvF group (119.8 versus 125.0 minutes, respectively, P = 0.868); the total fluoroscopy time was significantly shorter in the NFCV group (3.3 versus 16.6 minutes, P < 0.001). One patient in the CvF group experienced cardiac tamponade, requiring pericardial drainage. No major complications were encountered in the NFCV group. NFCV system, in conjunction with 3D-EMS, was safe and feasible for i-PVC/VT mapping and ablation. The system contributed to dramatically reduced fluoroscopy time, compared with CvF.

Bepridil Inhibits Premature Ventricular Complexes Induced by Cardio-Sympathetic Nerve Stimulation in a Canine Experimental Model

“…It is possible that such repolarization effects of this drug were associated with the inhibition of the SGstimulation induced PVC/NSVT. Since a likely mechanism of the PVC/NSVT was non-reentry rather than reentry, 23) we think that the primary reason for this antiarrhythmic effect is due to calcium current inhibition. However, it seems more reasonable to consider that multiple ionic current inhibition by bepridil prevented the SG-stimulation induced PVC/NSVT in this experimental study.…”

Results of catheter ablation in patients with idiopathic premature ventricular contractions depending on the use of fluoroscopy

“…За последнее десятилетие появились публикации от ряда исследователей об использовании нефлюороскопической катетерной аблации для лечения суправентрикулярных тахикардий, в первую очередь, правосторонних [5][6][7][8][9][10][11]. Однако на сегодняшний день очень мало работ об использовании нефлюороскопического подхода для лечения идиопатических желудочковых аритмий.…”

“…Частота ЖЭ различных локализаций в группах больных Приточный отдел ПЖ, абс. (%) 7 (7,8) 11 (11,8) 18 (9,8) Папиллярные мышцы ПЖ, абс.…”