Idiopathic ulcerative dermatitis in a cat with feline infectious peritonitis

Abstract

A 1‐year‐old, castrated, male, domestic short‐haired cat with pruritic, multifocal, crusted ulceration of the skin over the dorsal aspect of the neck and scapulae was presented. The cat also had a history of depression and anorexia. A causative agent for the lesion was not identified on a general dermatological examination. Histopathology revealed diffuse epidermal ulceration and loss with replacement by neutrophilic inflammation and necrotic debris. Idiopathic ulcerative dermatitis (IUD) was diagnosed based on history, physical examination and histopathology. To prevent self‐trauma and secondary bacterial infection, light bandages and glucocorticoid ointment were applied. After a month of management, the lesions markedly improved. Approximately 3 months after the initial presentation, the cat died; necropsy confirmed an IUD and non‐effusive (dry form) feline infectious peritonitis (FIP). This report describes a rare case of IUD in a cat with concurrent FIP. However, no association between IUD and FIP was found.

Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines

“…In one report [ 230 ], IUD was diagnosed in a cat with uveitis, and the small ulcer on the dorsal neck was positive for the FCoV antigen when tested by IHC. However, in another report of a cat with IUD [ 231 ], the FCoV antigen IHC of the skin was negative, although FIP was confirmed by IHC on kidney tissue. Priapism has been reported as a result of granulomatous changes in tissues surrounding the penis [ 232 ].…”

Is oclacitinib a suitable alternative to oral glucocorticoids for the control of pruritus in cats?

“…Several case reports describe apparent successful outcomes for oclacitinib treatment at varying dosages in individual cats with various skin conditions, where licensed medications appeared to be ineffective. [10][11][12][13][14][15][16][17][18][19] However, a small, uncontrolled study with a group of 12 cats diagnosed with feline atopic skin syndrome reported that twice daily administration at a dose licensed for dogs (0.42-0.56 mg/kg) was effective in less than 50 per cent of cats. 9 One possible explanation for the lower efficacy of the dose licensed for dogs when used in cats could be that the bioavailability and clearance of oclacitinib appear to be faster in cats than in dogs.…”

“…Several case reports describe apparent successful outcomes for oclacitinib treatment at varying dosages in individual cats with various skin conditions, where licensed medications appeared to be ineffective 10–19 . However, a small, uncontrolled study with a group of 12 cats diagnosed with feline atopic skin syndrome reported that twice daily administration at a dose licensed for dogs (0.42–0.56 mg/kg) was effective in less than 50 per cent of cats 9 …”

Cutaneous lesions and clinical outcomes in five cats after frunevetmab injections

“…Lesions have also been reported on the lateral neck and temporal areas. [16][17][18][19][20] While some cases of FIUD have been shown to respond to glucocorticoids, topiramate, oclacitinib, surgical resection, bandaging/prevention of self-trauma or environmental enrichment, some authors regard the prognosis as guarded, as lesions may be refractory to medical treatment or may recur despite surgical resection. [16][17][18][19][20][21][22] In the present case series, a range of responses was noted, from spontaneous resolution in case 4, to the principal case (case 1) in which the skin lesion was refractory to medical treatment and required surgical resection.…”