Idiopathic Thrombocytopenic Purpura

Scharfman, William B.

doi:10.1001/jama.1960.03020170001001

Cited by 23 publications

(2 citation statements)

References 7 publications

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“…Up to puberty there are then as many girls as boys. The male preponderance has not been observed in other reports (2,9,13), though a uniform sex distribution prior to puberty has been reported (12).…”

Section: Totalmentioning

confidence: 65%

Thrombocytopenia

Böttiger

Westerholm

1972

Journal of Internal Medicine

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An analysis has been made of 359 patients with thrombocytopenia—from a health service region in Sweden—in respect of sex, age, cause and course. The incidence of thrombocytopenia is 4.5 male and 7.4 female cases per 100 000 inhabitants and annum. In contradistinction to earlier reports, a large number of cases occur at high ages, probably due in particular to an increase in the number of drug‐induced cases. Drugs have caused 18% of all cases, but the main group (47%) must still, in the absence of an established cause, be denoted as idiopathic.

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Section: Totalmentioning

confidence: 65%

Thrombocytopenia

Böttiger

Westerholm

1972

Journal of Internal Medicine

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“…These antibodies (IgG) bind to the surface of platelets resulting in premature platelet destruction (Newman et al, 1989). In horses, the condition may be due to idiopathic thrombocytopenic purpura and autoimmune thrombocytopenia (Larson et al, 1983) or secondarily sequel to another disorder (Sellon et al, 1996a;Cohen & Carter, 1991). Equine infectious anemia virus has also been found to be associated with IMT (Sellon et al, 1996b).…”

Section: Equine Autoimmune Thrombocytopenia (Eat)mentioning

confidence: 99%

Autoimmune disorders in horses: the role of Insect Bite Hypersensitivity

2022

JoSVAS

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Autoimmune disorders are exaggerated immunologic responses to harmless antigens. The incidences of these conditions in animals specifically horses are on the increase. Autoimmune skin disorders of horses such as multi-systemic eosinophilic epitheliotrophic disease (MEED) and Pemphigus foliaceus (PF) are triggered by insect bite hypersensitivity principally due to Culicoides and Simulium species respectively. Other relatively uncommon skin disorders of horses include pemphigus vulgaris, cutaneous lupus erythematosus, bullous pemphigoid, systemic lupus erythematosus, and erythema multiforme. The roles of risk factors such as autoantibodies and changes associated with age in the immune system of equines such as immunosenescence and inflamm-aging, and the diagnosis, treatment, and management of some major autoimmune diseases of horses are discussed in this review. Additionally, we reviewed recent information on autoimmune thrombocytopenia in equines

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