Idiopathic Sporadic Onychomadesis: Case Report and Literature Review

Hardin, Jori; Haber, Richard M.

doi:10.1001/archdermatol.2012.81

Cited by 16 publications

(19 citation statements)

References 2 publications

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“…Onychomadesis is characterized by spontaneous detachment of the nail plate from the nail matrix, in which detachment begins at the proximal end of the nail bed, although not always, consequently leading to nail shedding. A vast variety of health conditions, mainly including infections and autoimmune diseases have been implicated in the etiology of onychomadesis [1,2]. It is well-known that thyroid diseases have significant cutaneous manifestations, some of which are distinctly linked with nails [3].…”

Section: Introductionmentioning

confidence: 99%

Onychomadesis secondary to autoimmune thyroid disease mimicking thyroid acropachy

Yorulmaz¹,

Yalçın²

2020

Our Dermatol Online

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Onychomadesis has been described as proximal separation of the nail plate from the nail matrix due to drastic insult to the matrix that induces a total arrest of matrix activity. A vast variety of health conditions, mainly including infections and autoimmune diseases have been implicated in the etiology of onychomadesis. However, up to now no published data is available on the association of autoimmune thyroid disease with onychomadesis. Here, we present a case of autoimmune thyroid disease induced onychomadesis in a 85-year-old woman. Moreover, we highlighted a distinct feature of the patient in that nail findings of the patient exceptionally resemble thyroid acropachy, which is a very rare manifestation of autoimmune thyroid disease.

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Section: Introductionmentioning

confidence: 99%

Onychomadesis secondary to autoimmune thyroid disease mimicking thyroid acropachy

Yorulmaz¹,

Yalçın²

2020

Our Dermatol Online

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“…Recurrent onychomadesis is uncommon and suggests temporally separated, repetitive matrix insults. Some recurrent cases have been attributed to autoimmune disease relapses or reported as familial or idiopathic [7]. A patient with recurrent seasonal onychomadesis of the great toenails is reported.…”

Section: Introductionmentioning

confidence: 99%

Seasonal Onychomadesis of the Great Toes

Pearson

Daniel

2017

Skin Appendage Disord

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Onychomadesis occurs when the proximal nail plate becomes unattached to the underlying structures. When only one or a few nails are involved, the cause is usually physical trauma. A 23-year-old female presented with a 4-year history of recurrent onychomadesis involving her bilateral great toes that occurred during the springtime. While recurrent trauma from winter shoes or athletic activities may be a contributing factor, our patient was convinced that wearing tight-fitting socks during winter nights was the primary pathophysiologic process. By wearing socks only during the days and decreasing the amount of time the nails spent traumatized due to pressure, the patient's recurrent condition was eliminated.

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“…It can occur idiopathically, after trauma, or in association with serious systemic illnesses, infections and drugs reactions 1 2. The association between onychomadesis and HFMD was first proposed by Clementz et al ,3 with recent studies of HFMD outbreaks in Spain and Finland providing further supporting evidence 4…”

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confidence: 95%