Idiopathic Small Intestinal Disease in the Tropics

Baker, S. J.

doi:10.1007/978-1-4613-3424-8_7

Cited by 4 publications

(2 citation statements)

References 206 publications

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“…Unlike infectious diarrheal illness in these regions, children are less frequently affected by TS [8,24]. However, disease in children is similar in all aspects to that in adults.…”

Section: Epidemiologymentioning

confidence: 99%

“…Deposition of collagen in the basement membrane and lipid droplets adjacent to the epithelial cells is seen in TS. The pattern of lipid accumulation is different in patients with TS compared with normal subjects and patients with celiac sprue [24,40]. Structural abnormalities similar to those in small intestinal pathology may be present in colonic epithelial cells with impairment of water and electrolyte absorption [41,42••] in patients with TS.…”

Section: Pathologymentioning

confidence: 99%

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Tropical sprue

Nath

2005

Curr Gastroenterol Rep

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Tropical sprue (TS) is a clinical entity of unknown etiology characterized by an acquired chronic diarrheal illness and malabsorption that affects indigenous inhabitants and expatriates, either long-term residents or short-term visitors, in the tropical countries. The exact pathogenetic sequence of TS remains incompletely characterized. Bacterial overgrowth, disturbed gut motility, and hormonal and histopathologic abnormalities contribute to the development of TS in a susceptible host. Treatment with tetracycline and folate is effective in some patients, although relapses after treatment are common. Research in the areas of microbial factors, pathogenesis, immunogenetics, and hormonal and immune regulation, using modern diagnostic techniques, may be able to settle some of the unanswered issues and open new venues for diagnosis, prevention, and treatment of tropical sprue.

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“…Unlike infectious diarrheal illness in these regions, children are less frequently affected by TS [8,24]. However, disease in children is similar in all aspects to that in adults.…”

Section: Epidemiologymentioning

confidence: 99%

Section: Pathologymentioning

confidence: 99%

Tropical sprue

Nath

2005

Curr Gastroenterol Rep

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Aetiology and Pathogenesis of Postinfective Tropical Malabsorption (Tropical Sprue)

Cook

1984

The Lancet

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William Hillary and sprue in the Caribbean: 230 years later.

Bartholomew¹

1989

Gut

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William Hillary and sprue in the Caribbean: 230 years later COURTENAY BARTHOLOMEW Aretaeus from Cappadocchia, which was at that time part of the Greek Empire and is now part of present day Turkey, left us an account of sprue in Chapter VII of his extant works entitled 'On the Coeliac Affection'.' This was in the second or third century AD and probably refers to coeliac sprue. More than a millenium later, in 1747, an Englishman, more specifically a Yorkshireman, migrated to the Caribbean island of Barbados which had been a British colony since 1627. This Yorkshireman, Dr William Hillary, came to practice medicine but was also a systematic observer of the weather and its relationship to disease. He began these observations in Ripon in England and resumed them in Barbados. In 1759, he published one of the earliest books in the English medical literature on tropical diarrhoeal disease which occurred more frequently in native Barbadians than in white settlers. It carried the

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Idiopathic Small Intestinal Disease in the Tropics

Cited by 4 publications

References 206 publications

Tropical sprue

Tropical sprue

Aetiology and Pathogenesis of Postinfective Tropical Malabsorption (Tropical Sprue)

William Hillary and sprue in the Caribbean: 230 years later.

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