2011
DOI: 10.1002/nau.20983
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Idiopathic Parkinson's disease patients at the urologic clinic

Abstract: The irritative urinary symptoms manifested urodynamically as neurogenic detrusor overactivity are more common in IPD patients than obstructive symptoms. These irritative symptoms deteriorate progressively with the disease severity and significantly affect the quality of life of these patients. The International Prostate Symptom Score is a valuable tool in evaluating the urinary dysfunction in such patients.

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Cited by 47 publications
(39 citation statements)
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“…1,4,6 The current management involves not only palliation of neurological and motor deterioration, but also improvement of NDO symptoms significantly affecting the QoL of patients. 6 Different managements, including the use of pharmacotherapy and surgery have been proposed, but they usually do not restore functional synergy.…”
Section: 5 Lutsmentioning
confidence: 99%
See 1 more Smart Citation
“…1,4,6 The current management involves not only palliation of neurological and motor deterioration, but also improvement of NDO symptoms significantly affecting the QoL of patients. 6 Different managements, including the use of pharmacotherapy and surgery have been proposed, but they usually do not restore functional synergy.…”
Section: 5 Lutsmentioning
confidence: 99%
“…LUTS in PD have not been shown as a significant threatening cause of upper urinary tract involment because of patients with PD suffers from NDO bladder without detrusor sphincter dysynergia (DSD). 4…”
Section: Introductionmentioning
confidence: 99%
“…Reduction in nigrostriatal dopamine (specifically, diminished or absent D1 receptor stimulation) leads to partial or total disconnection of the micturition reflex from voluntary control and, in turn, uninhibited bladder contractions in the presence of negligible volumes of urine (Blackett et al, 2009;Gray, Stern, & MaloneLee, 1995;Katz & Greenstein, 1989;Ransmayr et al, 2008;Singer, 2005;Singer, Weiner, & Sanchez-Ramos, 1992;Siroky, 2003). This is generally referred to as detrusor hyperreflexia or detrusor overactivity (DH/DO), the most common urodynamic pattern in patients with PD (Chancellor & Blaivas, 1991;Katz & Greenstein, 1989;Fitzmaurice et al, 1985;Ragab & Mohammed, 2011;Siroky, 2003). Symptoms reported by patients with PD and DH/DO include urinary urgency and frequency, nocturia, and urge UI (Araki & Kuno, 2000;Blackett et al, 2009;Ragab & Mohammed, 2011;Ransmayr et al, 2008;Sakakibara et al, 2001a;Stacy, 1999).…”
Section: Background/literature Reviewmentioning
confidence: 99%
“…This is generally referred to as detrusor hyperreflexia or detrusor overactivity (DH/DO), the most common urodynamic pattern in patients with PD (Chancellor & Blaivas, 1991;Katz & Greenstein, 1989;Fitzmaurice et al, 1985;Ragab & Mohammed, 2011;Siroky, 2003). Symptoms reported by patients with PD and DH/DO include urinary urgency and frequency, nocturia, and urge UI (Araki & Kuno, 2000;Blackett et al, 2009;Ragab & Mohammed, 2011;Ransmayr et al, 2008;Sakakibara et al, 2001a;Stacy, 1999).…”
Section: Background/literature Reviewmentioning
confidence: 99%
“…The irritative urinary symptoms manifested urodynamically as neurogenic detrusor overactivity are more common in IPD patients than obstructive symptoms. 46 One study investigated the LUTS and urodynamic and cystometric findings in PD, dementia with Lewy bodies, and Alzheimer's disease (AD). Urgency and urge incontinence are more prevalent in dementia with Lewy bodies than in PD and AD, whereas mean voided volume, free flow, cystometric bladder capacity, and detrusor pressure were similar in the groups; DO in 92% of the patients with dementia with Lewy bodies, 46% of the patients with PD, and 40% of the patients with AD.…”
Section: Oab Questionnairesmentioning
confidence: 99%