Idiopathic normal pressure hydrocephalus

“…The main clinical features are imbalance and gait disturbance with or without cognitive decline and urinary incontinence. MR or CT scans show communication between the enlarged ventricles and the subarachnoid space of the brain [14]. The treatment consists of surgically placing a shunt system which passes CSF into a silicone tube from the ventricles of the brain to the abdominal cavity.…”

Section: Introductionmentioning

confidence: 99%

Adaptive method for assessment of cerebrospinal fluid outflow conductance

et al. 2007

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Outflow conductance (C(out)) is important for predicting shunt responsiveness in patients with suspected idiopathic adult hydrocephalus syndrome (IAHS). C (out) is determined by performing an infusion test into the cerebrospinal fluid system, and the reliability of the test is dependent on the measurement time. The objective of this study was to develop an adaptive signal analysis method to reduce the investigation time, by taking the individual intracranial pressure variations of the patient into consideration. The method was evaluated on 28 patients with suspected IAHS. The results from full time investigations (60 min) were compared to the results of the new algorithm. Applying the new adaptive method resulted in a reduction of mean investigation time by 14.3 +/- 5.9 min (mean +/- SD), p<0.01. The reduction of reliability in the C(out) estimation was found clinically negligible. We thus recommend this adaptive method to be used when performing constant pressure infusion tests.

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“…To obtain a large span of brain volumes, we chose 41 healthy elderly volunteers (mean age, 70 Ϯ 6 years; 24 women) and 20 patients with ventriculomegaly due to possible or probable idiopathic normal pressure hydrocephalus (mean age, 73 Ϯ 7 years; 9 women). 15,16 The study was approved by the university ethics board.…”

Section: Subjectsmentioning

confidence: 99%

MR Imaging of Brain Volumes: Evaluation of a Fully Automatic Software

Ambarki

Wåhlin²,

Birgander³

et al. 2010

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:Automatic assessment of brain volumes is needed in research and clinical practice. Manual tracing is still the criterion standard but is time-consuming. It is important to validate the automatic tools to avoid the problems of clinical studies drawing conclusions on the basis of brain volumes estimated with methodologic errors. The objective of this study was to evaluate a new commercially available fully automatic software for MR imaging of brain volume assessment. Automatic and expert manual brain volumes were compared.

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Idiopathic normal pressure hydrocephalus

Cited by 83 publications

References 97 publications

Hydrocephalus: An Overview

Hydrocephalus: An Overview

Adaptive method for assessment of cerebrospinal fluid outflow conductance

MR Imaging of Brain Volumes: Evaluation of a Fully Automatic Software

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