Idiopathic Myointimal Hyperplasia of the Mesenteric Veins

Patel, Aashay; Schneider, Yecheskel; Saumoy, Monica; Maltz, Charles; Yeo, Heather; Jessurun, José; Wan, David

doi:10.14309/crj.2016.57

Cited by 42 publications

(17 citation statements)

References 3 publications

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“…Of the 34 cases of IMHMV that occurred in men, usually in late middle age (median age at diagnosis 62 years) . Many of these patients, including our patient, have cardiovascular risk factors or disease .…”

Section: Discussionmentioning

confidence: 79%

“…The etiology of this nonthrombotic occlusion of mesenteric veins is poorly understood. First described by Genta and Haggitt in 1991, 33 reported cases of IMHMV have now been reported (Table ), and it is likely there are many more misdiagnosed or not reported.…”

Section: Discussionmentioning

confidence: 99%

“…The non‐specific presenting symptoms include diarrhea, usually bloody; lower abdominal pain; and weight loss, resulting in the frequent misdiagnosis of IBD. Patients are often treated with corticosteroids or other IBD therapies such as 5‐aminosalicylates, immunomodulators, or biologic agents …”

Section: Discussionmentioning

confidence: 99%

“…The radiological appearance of IMHMV on computed tomography (CT) is suggestive of colitis, with thick, edematous bowel and fat stranding . Strictures in the sigmoid colon have also been reported .…”

Section: Discussionmentioning

confidence: 99%

“…In three cases, the diagnosis of IMHMV was reached prior to surgical resection via endoscopy and histology . Most patients underwent surgical resection due to significant morbidity and a lack of improvement with corticosteroids or other IBD treatments.…”

Section: Discussionmentioning

confidence: 99%

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Idiopathic myointimal hyperplasia of the mesenteric veins: Case report and review of the literature

et al. 2019

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In 1991, Genta and Haggitt described four patients with segmental ischemic colitis caused by idiopathic myointimal hyperplasia in the small mesenteric veins (IMHMV). There are now 33 published cases of IMHMV in the literature; however, this condition is still sufficiently rare that it poses a diagnostic challenge to pathologists and clinicians and is often clinically or histologically confused with inflammatory bowel disease (IBD) or ischemic colitis. IMHMV is characterized by intimal smooth muscle hyperplasia resulting in thickened small and medium‐sized mesenteric veins (with arterial sparing). Clinically, it presents with symptoms that mimic IBD, such as bloody diarrhea, abdominal pain, and weight loss. Surgical resection appears to be curative. The present case describes a 63‐year‐old Vietnamese man with cardiovascular risk factors who was diagnosed with IMHMV after many months of severe symptoms. A review of the current literature follows the case report.

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Section: Discussionmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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