Idiopathic intracranial hypertension in the Middle East: A growing concern

Almarzouqi, Sumayya J.; Morgan, Michael L.; Lee, Andrew G.

doi:10.1016/j.sjopt.2014.09.013

Cited by 29 publications

(43 citation statements)

References 42 publications

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“…The loss of vision in patients with PTCS is thought to be due to papilloma and secondary optic neuropathy, and almost all patients have papilledema. Papilledema is usually bilateral and symmetric, but may be mildly asymmetric or unilateral (10%) (9). In our study, unilateral papilledema was detected in 4 (11.8%) patients.…”

Section: Discussionsupporting

confidence: 46%

“…The disease results in blindness in about 10% of patients. Other symptoms that may be seen include blurred vision, loss of vision, diplopia (due to undefined sixth cranial nerve paralysis), pulsatile tinnitus, and vertigo (6,8,9). Headache can be typically bilateral frontal or retro-orbital, pulsating or in the form of pressure sensation.…”

Section: Discussionmentioning

confidence: 99%

“…Peripheral vision loss is insidious and many patients are unaware of minor deficits because central vision is preserved until late periods. There may also be a rare acute loss of vision (9). The sixth cranial nerve is the most affected cranial nerve from increased ICP, which results in binocular horizontal diplopia.…”

Section: Discussionmentioning

confidence: 99%

“…As seen, there are no pathognomonic radiologic findings, although there are many radiologic findings that are suggestive of PTCS (10). Treatment depends on symptoms and status of loss of vision (9). The main goal of the treatment is to prevent vision loss and to reduce symptoms associated with increased ICP (10).…”

Section: Discussionmentioning

confidence: 99%

“…Asymptomatic patients with normal vision and minimal papillary edema are followed up. The treatment protocol is conservative in patients with normal vision and analgesic-controlled headaches (9). The treatment protocol consists of medical, CSF drainage via LP, and surgical methods.…”

Section: Discussionmentioning

confidence: 99%

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Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital

Arslan¹,

Arıkanoğlu²,

Akıl³

2017

tnd

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Objective: Pseudotumor cerebri syndrome (PTCS) is characterized by symptoms and signs of increased intracranial pressure without ventriculomegaly, intracranial tumor or mass. This study aimed to explore and analyze 34 patients with PTCS according to age, sex, symptoms of the disorder, cranial magnetic resonance images findings, etiology, and treatment. Materials and Methods:A total of 34 patients who were diagnosed as having PTCS and followed up between January 2011 and August 2016 by Dicle University Medical School Neurology Department were included in this study. PTCS was diagnosed in accordance with the modified Dandy criteria. Results:Thirty-four patients were identified as having PTCS. Twenty-one (91.2%) had headache, 19 (55.9%) had blurred vision, 6 (17.6%) had diplopia, 2 (5.9%) had vertigo, 1 (2.9%) had tinnitus, and 1 (2.9%) had numbness of the face. Twenty-seven patients were diagnosed as having idiopathic intracranial hypertension, 21 (61.8%) had no etiologic factors. Six (17.6%) patients were obese, one of whom had recently gained weight and another had polycystic ovary syndrome. Seven patients were thought to have secondary PTCS with the following etiologic factors: 2 (5.9%) patients had Hashimoto's thyroiditis, 1 (2.9%) had a history of all-trans retinoic acid intake due to a malignancy, 1 (2.9%) had choroid plexus granuloma, 2 (5.9%) had sinus venous thrombosis, and 1 (2.9%) had Familial Meditteranian Fever.Conclusion: Although PTCS was described many years ago, its physiopathology and exact treatment procedures are not clearly understood. The most important target of its treatment is to prevent loss of vision and improve symptoms. With a better understanding of its pathophysiology, effective treatment protocols will be developed. Keywords: Idiopathic intracranial hypertension, pseudotumor cerebri syndrome, headacheAmaç: Psödotümör serebri sendromu (PTSS) ventrikülomegali, intrakraniyal tümör veya kitle olmaksızın intrakraniyal basıncın (İKB) arttığı bir sendromdur. Bu çalışmada kliniğimizde PTSS tanısı ile takip edilen 34 hastanın yaş, cinsiyet dağılımı, semptomları, kraniyal manyetik rezonans görüntüleme bulguları, etiyolojileri ve tedavileri tartışılmaktadır. Gereç ve Bulgular:Olguların 31'inde (%91,2) baş ağrısı, 19'unda (%55,9) bulanık görme, 6'sında (%17,6) diplopi, 1'inde (%2,9) tinnitus, 1'inde (%2,9) yüzde uyuşma, 2'sinde (%5,9) vertigo yakınması vardı. Yirmi yedi hasta idiyopatik intrakraniyal hipertansiyon (İİH) olarak kabul edildi. Yirmi bir hastada (%61,8) etiyoloji saptanamadı. Altı hastada (%17,6) obezite, bunların 1 tanesinde yakın zamanda kilo alma öyküsü, 1 tanesinde de polikistik over sendromu saptandı. Yedi hastada sekonder PTSS düşünüldü. Sekonder sebepler olarak; 2 hastada (%5,9) Hashimoto tiroiditi, 1 hastada (%2,9), malignite nedeniyle all-trans retinoik asit kullanımı, 1 hastada (%2,9) koroid pleksus granülomu, 2 hastada (%5,9) sinüs trombozu, 1 hastada (%2,9) Ailesel Akdeniz Ateşi etiyolojik neden olarak saptandı. Clinical and Demographic Features of Pseudotumor

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Section: Discussionsupporting

confidence: 46%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital

Arslan¹,

Arıkanoğlu²,

Akıl³

2017

tnd

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Stauungspapille

Biermann

2023

Springer Reference Medizin

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Can optic disc vessel density help in cases of residual disc elevation after shunt surgery in cases of idiopathic intracranial hypertension?

El-Haddad,

Ismael,

Shabaan

et al. 2024

Lasers Med Sci

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Aim To detect if we can use the reduction in the optic disc vessel density as an indicator to the reduction in intracranial tension in patients with residual optic disc elevation after shunt surgery as fundus examination in those cases is not conclusive. Patients and method 21 patients with papilledema due to idiopathic intracranial hypertension underwent shunt surgery. Full neurological and ophthalmological assessments were done. The optic disc vessel density was measured before and 3 months after surgery. Patients were then divided according to the resolution of papilledema into 2 groups: 1) Residual disc elevation group. 2) Completely resolved disc edema group. CSF pressure was measured via lumber puncture preoperative for all patients and 3 months post-operative only for patients with residual disc edema. A comparison between both groups was done. Results There was a highly statistically significant difference between the two groups as regard the papilledema grade (the residual disc elevation group had a higher grade of papilledema) with P-value=0.000. As regard the difference in the preoperative optic disc vessel density between the two groups, there were statistically significant differences (optic disc vessel density was more in the residual disc elevation group). As regard the postoperative optic disc vessel density, there were non-significant differences between the two groups in whole image, inside disc and peripapillary vessel density (either in macro or microvasculature). Conclusion The optic disc vessel density decreased with normal postoperative CSF opening pressure in cases with residual disc elevation postoperatively. Thus, in cases of residual optic disc swelling after shunt surgery, we can detect the reduction of intracranial pressure by the reduction in the optic disc vessel density which is a safe non-invasive technique. That may help in cases of residual disc elevation.

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Idiopathic intracranial hypertension in the Middle East: A growing concern

Cited by 29 publications

References 42 publications

Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital

Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital

Stauungspapille

Can optic disc vessel density help in cases of residual disc elevation after shunt surgery in cases of idiopathic intracranial hypertension?

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