Idiopathic intracranial hypertension and systemic lupus erythematosus: a case report and review of the literature

Barahona-Hernando, R; Ríos-Blanco, JJ; Méndez-Mesón, I; Pérez‐Valero, Ignacio; Soto-Abánades, CI; Noval, Susana; Carceller, Fernando; Robles‐Marhuenda, Ángel; Gil‐Aguado, Antonio

doi:10.1177/0961203309104429

Cited by 16 publications

(11 citation statements)

References 13 publications

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“…Few cases of idiopathic intracranial hypertension have been reported. 60% of cases reported in the literature are associated with antiphospholipid antibodies [79]. …”

Section: Ocular Manifestationsmentioning

confidence: 99%

Ocular Manifestations of Systemic Lupus Erythematosus: A Review of the Literature

Palejwala

Walia

Yeh

2012

Autoimmune Diseases

150

194

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About one-third of patients suffering from systemic lupus erythematosus have ocular manifestations. The most common manifestation is keratoconjunctivitis sicca. The most vision threatening are retinal vasculitis and optic neuritis/neuropathy. Prompt diagnosis and treatment of eye disease is paramount as they are often associated with high levels of systemic inflammation and end-organ damage. Initial management with high-dose oral or IV corticosteroids is often necessary. Multiple “steroid-sparing” treatment options exist with the most recently studied being biologic agents.

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“…Few cases of idiopathic intracranial hypertension have been reported. 60% of cases reported in the literature are associated with antiphospholipid antibodies [79]. …”

Section: Ocular Manifestationsmentioning

confidence: 99%

Ocular Manifestations of Systemic Lupus Erythematosus: A Review of the Literature

Palejwala

Walia

Yeh

2012

Autoimmune Diseases

150

194

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“…Interestingly, one notable feature of our case was that it occurred in a young male patient. Cases in the literature are largely limited to female patients; we found only three other cases describing IH and SLE in males [20][21][22] (Table 1). Comparing the cases of males with SLE-associated IH to females revealed some interesting distinctions (Table 2).…”

mentioning

confidence: 96%

Intracranial hypertension associated with systemic lupus erythematosus in a young male patient

Tse

Klein

2012

Lupus

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Systemic lupus erythematosus (SLE) is a chronic disease that affects multiple organ systems including the central nervous system. We present a case of a young male with a new diagnosis of SLE presenting as intracranial hypertension (IH). Review of the literature suggests an association between SLE and IH and prompts a reconsideration of the exclusion of IH from the American College of Rheumatology's accepted neuropsychiatric manifestations. In addition, our case is one of the few cases of IH and SLE in males. While the data are limited, SLE-associated IH in males may be different from that in females with respect to presentation and severity.

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“…The pathophysiology of IIH may include the impairment of CSF absorption and venous outflow, rather than an increase in CSF production (9). The pathogenesis of IIH in SLE patients is still unclear; however, some case reports showed that IIH develops in active SLE patients, and other previous reports suggested a possible relationship between anti-phospholipid antibodies (aPL) or antiphospholipid syndrome (APS) and IIH (6,10). Therefore, thrombosis and hypercoagulability may cause impaired CSF absorption and lead to IIH in patients with SLE.…”

Section: Discussionmentioning

confidence: 98%

Bilateral Abducens Nerve Palsy due to Idiopathic Intracranial Hypertension as an Initial Manifestation of Systemic Lupus Erythematosus

et al. 2016

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Idiopathic intracranial hypertension (IIH) is a syndrome of increased intracranial pressure and presents as an intractable headache, vomiting, and ophthalmologic manifestations. We herein report the case of a young girl who presented with bilateral abducens nerve palsy due to IIH as the onset of systemic lupus erythematosus (SLE). The patient was successfully treated with corticosteroid therapy. Our case lacked the typical symptoms of IIH, such as headache or nausea; therefore, it is necessary to carefully determine the cause of bilateral abducens nerve palsies. The development of IIH in SLE patients is a rare occurrence, but this manifestation should not be overlooked.

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Idiopathic intracranial hypertension and systemic lupus erythematosus: a case report and review of the literature

Cited by 16 publications

References 13 publications

Ocular Manifestations of Systemic Lupus Erythematosus: A Review of the Literature

Ocular Manifestations of Systemic Lupus Erythematosus: A Review of the Literature

Intracranial hypertension associated with systemic lupus erythematosus in a young male patient

Bilateral Abducens Nerve Palsy due to Idiopathic Intracranial Hypertension as an Initial Manifestation of Systemic Lupus Erythematosus

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