Idiopathic hypercalciuria in children?how valid are the existing diagnostic criteria?

Butani, Lavjay; Kalia, Alok

doi:10.1007/s00467-004-1470-8

Cited by 66 publications

(36 citation statements)

References 42 publications

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“…Hiperkalsiüri ve taş olgularında aile öyküsünde %40 oranında ürolitiyaz öyküsü vardır. 31,[81][82][83][84] İyi bir diyet öyküsü alınmalıdır. Hastanın sıvı ve tuz tü-ketimi, C vitamini veya D vitamini desteği, özel diyet (ketojenik diyet gibi) alıp almadığı sorgulanmalıdır.…”

Section: Nütrisyonel Nedenlerunclassified

Urolithiasis in Childhood: Review

Zeybek¹,

Orman²

2017

Turkiye Klinikleri J Pediatr

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Section: Nütrisyonel Nedenlerunclassified

Urolithiasis in Childhood: Review

Zeybek¹,

Orman²

2017

Turkiye Klinikleri J Pediatr

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“…Ayrıca idrar akım hızının yavaşlaması, üriner sistemde duraklaması ve rezidü idrar varlığı taş oluşumunu kolaylaştırır (23).…”

Section: Anatomik Ve Fonksiyonel üRiner Anomaliunclassified

Çocuklarda Üri̇ner Si̇stem Taş Hastaliği: Tani Ve Tedavi̇ / Urinary System Stone Disease in Children: Diagnosis and Treatment

Cetın¹,

Sav²,

Yıldız³

2015

Osmangazi̇ Journal of Medicine

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ÖZET: Üriner sistem taş hastalığı son yıllarda prevelansı artış gösteren önemli bir hastalıktır. Çocuklarda yüksek tekrarlama oranı nedeni ile son dönem böbrek hastalığına sebep olduğundan önemli bir morbidite nedenidir. Üriner sistem taş hastalığı Türk çocuklarında kronik böbrek hastalığının altında yatan sebeplerin %8'ini oluşturmaktadır. Metabolik ve genitoüriner sisteme ait anormallikler çocuklarda üriner sistem taşlarının oluşmasına yatkınlık yaratabilir. Metabolik bir risk faktörü saptama oranı, çocuklarda üriner sistem taşı olan yetişkinlerden daha yüksektir. Diyet, çevresel faktörler ve idrar yolu enfeksiyonları üriner sistem taşlarının oluşmasında rol oynayabilir. Tekrarlama özelliği nedeni ile metabolik faktörlerin taşı olan bütün çocuklarda araştırılması gereklidir. Erken tedavi ve risk faktörlerinin saptanması morbiditeyi azaltmada oldukça önemlidir. Böbrek taşı olan çocuklarda üriner sistem taş hastalığının tedavi amacı, böbrek fonksiyonlarını korumak için taşın ortadan kaldırılmasını, nükslerin engellenmesini ve metabolik problemlerin düzeltilmesini kapsamaktadır. Uygun tedavi taşın boyutuna, yerleşimine ve tipine, anatomik anormalliklerin varlığına göre seçilir. Medikal tedavi, yeni taşların oluşumunu ve mevcut taşların büyümesini önleyerek morbiditeyi azaltmaktadır. ANAHTAR KELİMELER: Üriner sistem taşı, çocukluk çağı, tanı, tedavi.ABSTRACT: Urinary system stone disease is a disease that there is a increase in the prevalence of the disease in recent years. This disease is an important cause of morbidity because it causes end stage renal disease due to high recurrence rate. Urinary system stone disease is the cause of 8% of the underlying etiological factors for development of chronic kidney disease in Turkish children. Metabolic and genitourinary anomalies can predispose to develop urinary system stones in children. The detection rate of metabolic risk factor is higher in children than adults with urinary system stone. Diet, environmental factors and urinary tract infections may play a role in the formation of urinary system stones. Because of its recurrent nature, the metabolic abnormalities should be investigated in all of the children with urinary system stone. Early treatment and determination of the risk factors are very important to reduce morbidity. The aim of treatment of pediatric urinary system stone disease includes eliminating the stone and preventing recurrence and the correction of metabolic problems for protection kidney functions. The appropriate treatment depends on the size, location and type of stone; the presence of anatomical abnormalities. Medical therapy reduces morbidity by preventing the growth of stone and the formation of new stones.

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“…Hypercalciuria is considered idiopathic (IH) when it is associated with a normal blood calcium level. 1 This disorder affects 5-10% of the pediatric population 2 and is usually related to a family history oflithiasis. 3 It is mainly classified as of renal or intestinal origin; however, its treatment does not change, regardless the subtype detected.…”

Section: Introductionmentioning

confidence: 99%

“…4 Yet, there is consensus regarding the implementation of a sequential therapy when IH is associated with the development of urinary tract infections, dysfunctional micturition, nephrolithiasis, nephrocalcinosis, and osteopenia. 1,2,5 The objectives of this article were: 1. To describe hypercalciuria response to sequential therapy.…”

Section: Introductionmentioning

confidence: 99%

Treatment of idiopathic hypercalciuria and its impact on associated diseases

Liern

Bohorquez²,

Vallejo³

2013

Arch Argent Pediat

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Idiopathic hypercalciuria may be associated with urinary tract infection, hematuria, nephrolithiasis and osteopenia. In order to describe the occurrence of these concurrent conditions related to the variation in urinary calcium and hypercalciuria response to sequential therapy, with a normal protein and low sodium diet, potassium citrate and hydrochlorothiazide; 46 patients older than 4 years, with no urinary tract diseases, sphincter control and normal blood creatinine values were followed-up during 43 months. Hypercalciuria was seen to be associated with kidney stones (EAR 47%; RR 3.3), hematuria (EAR 71%; RR 2.5), urinary tract infections (EAR 57%; RR 3), and osteopenia (EAR 33%; RR 3). A normal value of urinary calcium was achieved with sequential therapy in 43 patients, but during follow-up 32 patients discontinued treatment and hypercalciuria recurred in 44% of them, in association with hematuria and urinary tract infection. Conclusions. Sequential therapy reduced hypercalciuria and the incidence of associated diseases.

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Idiopathic hypercalciuria in children?how valid are the existing diagnostic criteria?

Cited by 66 publications

References 42 publications

Urolithiasis in Childhood: Review

Urolithiasis in Childhood: Review

Çocuklarda Üri̇ner Si̇stem Taş Hastaliği: Tani Ve Tedavi̇ / Urinary System Stone Disease in Children: Diagnosis and Treatment

Treatment of idiopathic hypercalciuria and its impact on associated diseases

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