Idiopathic generalized epilepsies

Caraballo, Roberto; Bernardina, Bernardo Dalla

doi:10.1016/b978-0-444-52891-9.00060-9

Cited by 16 publications

(12 citation statements)

References 29 publications

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“…Idiopathic generalized epilepsies account for nearly a third of all epilepsies and are genetically determined and affect otherwise healthy people of both sexes and all races. ey may start in infancy, childhood, or adolescence, but some have an onset in adulthood [12].…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Epilepsy in Lubumbashi, Democratic Republic of Congo

Mukuku

Nawej²,

Bugeme

et al. 2020

Neurology Research International

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Background. Epilepsy is one of the most common neurological conditions, but the majority of epilepsy patients in sub-Saharan countries do not receive appropriate treatment. In the Democratic Republic of Congo (DRC), particularly in Lubumbashi, very few epidemiological studies on epilepsy have emerged. This study aims to analyze demographic characteristics, semiology of epileptic seizures, and their etiologies in patients followed in hospital. Methods. This is a prospective descriptive study that enrolled 177 epileptic patients who performed a neurological consultation at the Centre Médical du Centre Ville (CMDC) in Lubumbashi (DRC) from January 1, 2016, to December 31, 2017. Results. The mean age of the patients was 20.0 years (range: 5 months and 86 years). The male sex was predominant (57.1%). The mean age at the seizure onset was 13.1 years, and the mean duration between onset of seizures and consultation was 83.5 months. The family history of epilepsy was present in 27.7%. Generalized tonic-clonic seizures were the most frequent (58.2%), followed by atonic generalized seizures (9.6%) and focal clonic seizures (8.5%). The etiology was found in 68 (38.4%) patients and was dominated by neurocysticercosis (26.5%), meningitis (25%), perinatal pathologies (20.6%), and head injury (20.6%). Conclusion. This study is a useful starting point from which health programs and health professionals can work to improve the diagnosis and quality of epilepsy management in our community.

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Section: Discussionmentioning

confidence: 99%

Epidemiology of Epilepsy in Lubumbashi, Democratic Republic of Congo

Mukuku

Nawej²,

Bugeme

et al. 2020

Neurology Research International

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“…The other seizure types include myoclonic, absence, and partial seizures. 50 They usually remit by 11 years of age. Development is usually unaffected and the inheritance is typically autosomal dominant.…”

Section: Generalized Epilepsy With Febrile Seizures Plusmentioning

confidence: 99%

Genetics of Pediatric Epilepsy

Hani

Mikati

2015

Pediatric Clinics of North America

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“…Существует комплекс косвенных доводов за предположительно генетический характер пароксизмальных состояний. Это нормальный неврологический статус пациента и, как правило, отсутствие у него когнитивного дефицита к моменту дебюта приступов, не отягощенный перинатальный анамнез, отсутствие значимых изменений при нейровизуализации [7,8]. Безусловно, приступы должны быть типичны именно для генетических эпилепсий.…”

Section: введение / Introductionunclassified

“…Видео-ЭЭГ-мониторинг с полиграфической записьюнеобходимый тест для диагностики эпилепсии любого происхождения, а в случае генетических эпилепсий он может быть единственно необходимым и достаточным при правильно выясненном анамнезе и четкой клинической картине [8][9][10]. В случае предположительно генетической эпилепсии одним из характерных, однако не патогномоничных исключительно для генетических форм, ЭЭГ-признаков являются генерализованные разряды спайков, полиспайков или пик/полипик-волн как иктальные, так и интериктальные (рис.…”

Section: введение / Introductionunclassified