Idiopathic generalised epilepsy of late onset: a separate nosological entity?

Abstract

Apart from age-related onset of seizure types and syndromes with a loose upper limit of onset age, patients with a late onset did not differ from their younger counterparts. These data do not support the view of IGE of late onset as a separate syndrome.

Reflex epilepsy induced by playing Go-stop or Baduk games

“…22,23 In a recent study, a limited number of late onset IGE patients manifested myoclonic (7.1%) and absence (14.3%) seizures. 24 In this study, six patients had focal findings in EEG, MRI, or semiology such as irrational speech, facial expression of laughter, smelling a strange odor, prominent automatisms, conscious head version, and unilateral clonic movements. A family history of epilepsy, which may be a clue for IGE, was not reported among the patients of this study.…”

Clinical genetic study in juvenile myoclonic epilepsy

“…GGE syndromes usually start in childhood and adolescence, although a number of studies suggest that adult onset is more common than generally realized. 8,9 Although childhood or juvenile onset is emphasized, the international classification does not define age of onset as a limit for GGE subsyndromes. Three families were multiplex and 10 were multiplex/multi-generation.…”

The electroencephalogram of idiopathic generalized epilepsy

“…Overall, there does not appear to be any difference in EEG characteristics between the two groups (Yenjun et al., 2003). Apart from the age of onset, there are no significant differences from classical IGE to recognize this entity as a distinct syndrome (Reichsoellner et al., 2010).…”