Idiopathic epidural lipomatosis associated with degenerative discopathy: Grand round presentation of unusual lumbar canal stenosis resolved by weight loss

Alsofyani, Mohammad A; Haignere, Vincent; Alsalmi, Sultan; Gille, Olivier; Vital, Jean-Marc; Pointillart, Vincent; Boissi, Louis; Obeid, Ibrahim

doi:10.4103/ajns.ajns_255_19

Cited by 5 publications

(5 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Weight reduction has been identified to have a positive impact in the treatment of obese patients with SEL. [ 11 17 18 19 20 21 22 23 24 ]…”

Section: Discussionmentioning

confidence: 99%

“…The treatment of SEL ranges from conservative management [ 11 17 18 19 20 21 22 23 24 25 26 ] to surgical excision. [ 5 21 25 26 27 ] There are many cases reported the resolution of SLE on losing weight either by a structured weight loss program and/or by the help of bariatric surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Weight reduction has been identified to have a positive impact in the treatment of obese patients with SEL. [11,[17][18][19][20][21][22][23][24] The treatment of SEL ranges from conservative management [11,[17][18][19][20][21][22][23][24][25][26] to surgical excision. [5,21,[25][26][27] There are many cases reported the resolution of SLE on losing weight either by a structured weight loss program and/ or by the help of bariatric surgery.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Resolution of idiopathic epidural lipomatosis after bariatric surgery: Case report and literature review

et al. 2021

Self Cite

View full text Add to dashboard Cite

Spinal epidural lipomatosis (SEL) is traditionally a rare disorder defined as an abnormal accumulation of unencapsulated epidural fat. SEL can be classified into idiopathic and secondary. We report a 46-year-old obese male with idiopathic epidural lipomatosis with a clinical picture of bilateral L5 and S1 radiculopathy, with an L5 and S1 distribution. Magnetic resonance imaging (MRI) showed epidural lipomatosis at L4, L5, and S1. After 2-year of sleeve gastrectomy, his bilateral sciatic radiculopathy disappeared, and updated MRI showed complete resolution of epidural lipomatosis. We present a case of an unusual epidural lipomatosis, resolved completely by bariatric surgery. This case report set out the effect of metabolic surgery on the local and systemic metabolic process.

show abstract

“…Weight reduction has been identified to have a positive impact in the treatment of obese patients with SEL. [ 11 17 18 19 20 21 22 23 24 ]…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Resolution of idiopathic epidural lipomatosis after bariatric surgery: Case report and literature review

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…10,11 In some cases, weight loss alone was sufficient to alleviate the clinical symptoms and reduce the volume of epidural adipose tissue. 12,13 Some scholars have suggested that for every percentage point increase in body weight, the likelihood of suffering from SEL increases by 13%. 14 Up to now, although many literature has shown that obesity has a clear correlation with SEL, most of them are isolated case reports and small sample case series.…”

Section: Introductionmentioning

confidence: 99%

Obesity is a risk factor for epidural lipomatosis: a meta-analysis

Yuan

et al. 2021

J Orthop Surg (Hong Kong)

View full text Add to dashboard Cite

Purpose: The purpose of this meta-analysis was to summarize the evidence of associations between obesity factors and spinal epidural lipomatosis (SEL) and to evaluate the strength and validity of these associations. Methods: Electronic databases such as Wiley Online Library, PubMed, Embase, Cochrane Library were searched and manual retrieval of references, the time limit was from the establishment of the database to May 2020. Methodological quality evaluations of the included studies were assessed using the bias risk assessment tool recommended by the Cochrane Guidelines. The RevMan 5.3 software was used for meta-analysis. Results: Finally, seven studies were included for meta-analysis, all of which were observational studies with mixed bias risk. These studies involved 807 patients, with an average age of 64 to 73.6 years, and 59.4 percent of the participants were male. The sample sizes for the included studies ranged from 28 to 288. The results of meta-analysis showed that high body mass index (BMI) was one of the factors affecting SEL ( P < 0.01, MD 1.37, 95% CI [0.81, 1.92]). All reviews had a high risk of bias, and the most common source of bias was that there was no strict unified case diagnosis standard between researches, and some studies (four items) did not clearly describe the confounders that they controlled. Conclusions: We suggest that physicians should consider high BMI as a factor leading to SEL, and to control body weight actively should be considered as the preferred treatment strategy before surgical intervention is conducted.

show abstract

“…In some cases, weight loss alone was su cient to alleviate the clinical symptoms and reduce the volume of epidural adipose tissue [12,13]. Some scholars have suggested that for every percentage point increase in body weight, the likelihood of suffering from SEL increases by 13% [14].…”

Section: Introductionmentioning

confidence: 99%

Obesity is a Risk Factor for Epidural Lipomatosis: A Meta-analysis

Zhang

Yuan

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Many studies have investigated the relationship between spinal epidural lipomatosis and obesity, no meta-analysis of studies have provided definitive evidence. To summarize the evidence of associations between obesity factors and spinal epidural lipomatosis (SEL) and to evaluate the strength and validity of these associations. Methods: Electronic databases such as Wiley Online Library, PubMed, Embase, Cochrane Library were searched and manual retrieval of references, the time limit was from the establishment of the database to May 2020. The included literature was case-control studies that reported body mass index (BMI) and SEL correlation, and excluded any primary and secondary tumors or other compression diseases in the spinal canal. Methodological quality evaluations of the included studies were assessed using the bias risk assessment tool recommended by the Cochrane Guidelines. The RevMan 5.3 software was used for meta-analysis. Results: Finally, ten studies were included for systematic review, all of which were observational studies with mixed bias risk. These studies involved 1,541 patients, with an average age of 54.9 to 73.6 years, and 60.2 percent of the participants were male. The sample sizes for the included studies ranged from 28 to 398. The results of meta-analysis showed that high BMI was one of the factors affecting SEL. All reviews had a high risk of bias, and the most common source of bias was that there was no strict unified case diagnosis standard between researches, and some studies (four items) did not clearly describe the confounders that they controlled. Conclusions: We suggest that physicians should consider obesity as a factor leading to SEL, and to control body mass index actively should be considered as the preferred treatment strategy before surgical intervention is conducted.

show abstract

Idiopathic epidural lipomatosis associated with degenerative discopathy: Grand round presentation of unusual lumbar canal stenosis resolved by weight loss

Cited by 5 publications

References 20 publications

Resolution of idiopathic epidural lipomatosis after bariatric surgery: Case report and literature review

Resolution of idiopathic epidural lipomatosis after bariatric surgery: Case report and literature review

Obesity is a risk factor for epidural lipomatosis: a meta-analysis

Obesity is a Risk Factor for Epidural Lipomatosis: A Meta-analysis

Contact Info

Product

Resources

About