Idiopathic chondrolysis of the hip.

Bleck, Eugene E.

doi:10.2106/00004623-198365090-00007

Cited by 60 publications

(56 citation statements)

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“…1,2 Several authors describe spontaneous resolution of the condition over time. 9,10,42 This is not our experience, with none of our patients responding to prolonged non-operative management. An interesting finding was that the ROM improved under general anaesthetic prior to surgery in all cases.…”

Section: Outcomementioning

confidence: 79%

“…38 Premature closure of the femoral capital physis 9 and protrusio acetabuli 39 is also documented. Late manifestations of the disease reflect the secondary degenerative changes of osteoarthritis.…”

Section: Imagingmentioning

confidence: 96%

“…4 Subsequently the condition was verified with reported cases from around the world. [5][6][7][8][9][10][11][12][13][14][15] Various treatment strategies have been advocated. Nonoperative treatment with non-steriodal anti-inflammatory drugs (NSAIDs), non-weight bearing and physiotherapy, including continuous passive motion (CPM), are used.…”

Section: Introductionmentioning

confidence: 99%

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Subtotal capsulectomy for idiopathic chondrolysis of the hip: A clinical, radiological and histological study

Laubscher¹,

Banderker²,

Pillay³

et al. 2016

SA orthop. j.

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Background: Idiopathic chondrolysis (IC) of the hip is a rare, disabling condition affecting mainly adolescent females. Cartilage necrosis results in a stiff, painful hip which in the majority of cases have a poor outcome. The aetiology still remains unknown and the treatment is controversial and relatively unsuccessful. Subtotal capsulectomy with soft tissue releases has been reported to give good results.

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Section: Outcomementioning

confidence: 79%

Section: Imagingmentioning

confidence: 96%

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Subtotal capsulectomy for idiopathic chondrolysis of the hip: A clinical, radiological and histological study

Laubscher¹,

Banderker²,

Pillay³

et al. 2016

SA orthop. j.

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“…Early in the course of illness however, no changes on x-ray may be identified. Eventually, subchondral cysts, osteopenia, and osteophytes with sclerosis may be identified [2,3]. Chondrolysis is often limited to one joint.…”

Section: Discussionmentioning

confidence: 99%

“…The initial autoimmune reaction to cartilage results in synovitis that further destroys cartilage. Patients with no clear etiology have also been diagnosed with chondrolysis [2,3]. Idiopathic chondrolysis typically occurs in black female adolescents.…”

Section: Etiologymentioning

confidence: 99%

Juvenile Idiopathic Chondrolysis of the Hip

AS¹,

Hawkes²

2016

J Trauma Treat

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Effect of oral diacerein (DAR) in an experimental hip chondrolysis model

Kitadai

Takahashi

Straus

et al. 2006

Journal Orthopaedic Research

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We aimed to reproduce the articular cartilage structural changes in a joint exposed to a metallic implant as in the adolescent pinned hip with persistent joint penetration and secondly, to test the effect of an interleukin inhibitor, diacerein (DAR) in the ensuing articular cartilage lesion. Twenty immature beagles were submitted to a surgical K-wire implantation in the hip with the material left in the joint space for 6 months. Twelve animals were sacrificed for histological and biochemical tests. Eight animals were sacrificed at 10 months (half of them treated with DAR) and analyzed by scanning electron microscopy (SEM) and biochemistry of the articular cartilage. Preoperative and monthly C3 and C4 complement and immunoglobulins serum levels were determined. The histological and the electrophoretic profile changes were significative at 6 months. At 10 months the migration profile (CaCl 2 ) recovered to normal levels in the operated hip and the SEM scores for the acetabulum were similar to the non operated control hip after treatment. The serum level of IgA was elevated at the 4th and 6th month postoperatively. The persistence of a metallic implant resulted in degenerative changes parallel to that described for hip chondrolysis as a complication of in-situ pinning; and the cartilage lesion improved with DAR treatment. ß

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Idiopathic chondrolysis of the hip.

Cited by 60 publications

References 0 publications

Subtotal capsulectomy for idiopathic chondrolysis of the hip: A clinical, radiological and histological study

Subtotal capsulectomy for idiopathic chondrolysis of the hip: A clinical, radiological and histological study

Juvenile Idiopathic Chondrolysis of the Hip

Effect of oral diacerein (DAR) in an experimental hip chondrolysis model

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