Identifying transcriptomic profiles in ovine spleen after repetitive vaccination
Aitor Guisasola-Serrano,
Martin Bilbao-Arribas,
Endika Varela-Martínez
et al.
Abstract:Aluminum hydroxide has long been employed as a vaccine adjuvant for its safety profile, although its precise mechanism of action remains elusive. In this study, we investigated the transcriptomic responses in sheep spleen following repetitive vaccination with aluminum adjuvanted vaccines and aluminum hydroxide alone. Notably, this work represents the first exploration of the sheep spleen transcriptome in such conditions. Animals were splitted in 3 treatment groups: vaccine group, adjuvant alone group and contr… Show more
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