Abstract:Epigenetic modifications like chromatin remodeling play a vital role in regulating sepsis immunity. Understanding the role of chromatin remodeling in sepsis can help identify new potential therapeutic targets. Differentially expressed chromatin remodeling-related genes (DE-CRRGs) were identified between the sepsis and normal groups in GSE65682. LASSO regression, SVM, and random forest algorithms were employed to screen out six hub genes. The abundance of different immune cells in the two groups was determined … Show more
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