2005
DOI: 10.1016/j.jacc.2004.06.078
|View full text |Cite
|
Sign up to set email alerts
|

Identifying high-risk asymptomatic diabetic patients who are candidates for screening stress single-photon emission computed tomography imaging

Abstract: High-risk findings on stress SPECT imaging were present in 18% of asymptomatic diabetic patients without known CAD. Patients with high-risk scans had a high prevalence of severe CAD and a high annual mortality rate. ECG Q waves and/or evidence of PAD identified the most suitable candidates for screening.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

10
94
1
2

Year Published

2006
2006
2016
2016

Publication Types

Select...
9

Relationship

1
8

Authors

Journals

citations
Cited by 196 publications
(107 citation statements)
references
References 36 publications
10
94
1
2
Order By: Relevance
“…Importantly, although a normal MPS study is generally associated with a low risk (< 1% annual risk of cardiac death or myocardial infarction), the challenge in a diabetic population is to define the elusive "low-risk" patient. To date, reports have consistently shown that normal MPS in diabetic populations is not associated with this low level of risk and, in direct comparisons, patients with diabetes are at significantly greater risk than nondiabetics with normal MPS [24,[26][27][28][29]. Similarly, in the setting of an abnormal MPS, the risk conferred by any given extent and severity of perfusion abnormality is greater in patients with diabetes than in nondiabetics.…”
Section: Prognosis Of Silent Cad In Diabetic Patientsmentioning
confidence: 97%
See 1 more Smart Citation
“…Importantly, although a normal MPS study is generally associated with a low risk (< 1% annual risk of cardiac death or myocardial infarction), the challenge in a diabetic population is to define the elusive "low-risk" patient. To date, reports have consistently shown that normal MPS in diabetic populations is not associated with this low level of risk and, in direct comparisons, patients with diabetes are at significantly greater risk than nondiabetics with normal MPS [24,[26][27][28][29]. Similarly, in the setting of an abnormal MPS, the risk conferred by any given extent and severity of perfusion abnormality is greater in patients with diabetes than in nondiabetics.…”
Section: Prognosis Of Silent Cad In Diabetic Patientsmentioning
confidence: 97%
“…Rajagopalan et al examined angiographic findings and mortality rates in 826 asymptomatic diabetic patients with respect to MPS findings [24,25]. The mortality rate in high-risk patients was 5.9%, in intermediate-risk patients 5.0%, and in low-risk patients 3.6% (p < 0.001 for differences between groups).…”
Section: Prognosis Of Silent Cad In Diabetic Patientsmentioning
confidence: 99%
“…209,210 Although it is important to individualize clinical decision making, widespread screening for silent CAD in diabetes mellitus cannot be recommended at this time. 209 A variety of CAD screening tests [211][212][213][214][215][216][217][218][219][220][221][222][223][224][225][226][227][228][229] are available (Table 8). These include the simple, inexpensive, and noninvasive resting ECG, which may detect evidence of prior myocardial injury or ischemia.…”
Section: Subclinical Cad Assessmentmentioning
confidence: 99%
“…Patients should have baseline ECGs to evaluate for Q waves, ST‐T changes, T wave inversions, and left bundle branch block, which previously have been shown to be predictive of CAD 25. Exercise ECG is not recommended, given abnormal baseline ECGs and overall poor exercise tolerance in this patient population.…”
Section: Cad In Patients With Esrdmentioning
confidence: 99%