Identifying gray matter alterations in Cushing's disease using machine learning: An interpretable approach
Yue Long,
Jie Ren,
FuChao Cheng
et al.
Abstract:BackgroundCushing's Disease (CD) is a rare clinical syndrome characterized by excessive secretion of adrenocorticotrophic hormone, leading to significant functional and structural brain alterations as observed in Magnetic Resonance Imaging (MRI). While traditional statistical analysis has been widely employed to investigate these MRI changes in CD, it has lacked the ability to predict individual‐level outcomes.PurposeTo address this problem, this paper has proposed an interpretable machine learning (ML) framew… Show more
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