Identifying CSF using urine glucose dipstick testing

Hamilton, R.; Young, Steven J.

doi:10.1016/j.ijoa.2007.01.008

Cited by 4 publications

(3 citation statements)

References 3 publications

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“…Urine test strips are indeed recognized as a first-line diagnostic instrument, characterized by being easy-to-use and able to provide quick, reliable information about the urine composition under several pathological conditions. In humans, urine glucose dipstick tests have also been used to identify the cerebrospinal fluid [ 24 ] to underline the usefulness of this tool for the investigation of biological fluids different from urines.…”

Section: Introductionmentioning

confidence: 99%

Clinical Trial on the Usefulness of On-Site Evaluation of Canine Fetal Fluids by Reagent Test Strip in Puppies at Elective Caesarean Section

Fusi

Bolis

Probo

et al. 2021

Biology

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The reagent urinary test strips (TS) marketed for urines represent the first-line diagnostic tool in many instances. Therefore, the aim of the study was to assess the usefulness of TS for the on-field evaluation of fetal fluids’ composition in newborn dogs at elective caesarean section. Of a total of 137 puppies born at term, 127 survived and 10 did not survive. One hundred and thirteen amniotic and 107 allantoic samples from surviving newborns were collected, and 8 amniotic and allantoic fluids were collected from the non-surviving newborns and assessed by strips. Significantly lower amounts of amniotic glucose and higher amounts of amniotic and allantoic nitrites, amniotic protein, allantoic urobilinogen, and amniotic bilirubin concentrations were found in non-surviving when compared to surviving newborns. In the surviving ones, higher specific gravity and bilirubin concentrations, and lower pH, were found in allantoic than in amniotic fluids. Higher amniotic and allantoic glucose concentrations, higher amniotic and allantoic pH, and lower amniotic and allantoic protein concentrations were found in medium/large- than in small-sized puppies. The TS allowed the quick evaluation of fetal fluids in puppies at birth. The differences between surviving and non-surviving puppies seem to suggest that the on-site analysis of fetal fluids’ composition by TS could represent a first-line diagnostic tool in the field of canine neonatology, allowing the quick recognition of puppies needing assistance as a complementary tool for clinical evaluation.

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Section: Introductionmentioning

confidence: 99%

Clinical Trial on the Usefulness of On-Site Evaluation of Canine Fetal Fluids by Reagent Test Strip in Puppies at Elective Caesarean Section

Fusi

Bolis

Probo

et al. 2021

Biology

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“…6 Various bedside tests have been described for confirming whether the fluid is CSF including analyzing the fluid's temperature, density, pH, presence of glucose, and whether the fluid precipitates with thiopental (an alkaline solution). 6 Various bedside tests have been described for confirming whether the fluid is CSF including analyzing the fluid's temperature, density, pH, presence of glucose, and whether the fluid precipitates with thiopental (an alkaline solution).…”

Section: Discussionmentioning

confidence: 99%

Cerebrospinal Fluid Glucose Measurement at Point-of-Care

Thomas¹,

Halstead²,

Douglas³

et al. 2012

Point of Care: The Journal of Near-Patient Testing &Amp; Technology

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The ability to confirm that the fluid obtained during attempted spinal anesthesia after failed epidural anesthesia is cerebrospinal fluid (CSF) would be useful to the obstetric anesthesiologist. This study was designed to determine whether 3 point-of-care glucose devices (Precision Xtra [Abbott Point of Care], StatStrip Glucose Monitor [Nova Biomedical], and ACCU-CHEK Inform II [Roche Diagnostics]) would reliably measure glucose in CSF during routine spinal anesthesia for cesarean section. A sample of CSF was removed after dural puncture, and glucose was tested using all 3 devices at point-of-care. Results were compared with laboratory CSF glucose measurement (Vitros instruments [Ortho Clinical Diagnostics]). Ease of use of the 3 glucose monitors in the operating room setting and the relationship between blood and CSF glucose levels were also examined. Thirty women were studied. With one exception, blood glucose levels were normal. The StatStrip Glucose Monitor and the ACCU-CHEK Inform II gave similar results of CSF glucose as a percentage of blood glucose in most samples. There was no correlation between the length of fast and CSF glucose results. Both the StatStrip Glucose Monitor and the ACCU-CHEK Inform II showed good agreement with laboratory CSF glucose. There was a significant positive bias with the Precision Xtra device. This study confirmed that some point-of-care devices can measure CSF glucose level reliably in the operating room setting. Further studies are needed to see if this will prove useful during attempted spinal anesthesia after failed epidural anesthesia.

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“…[1][2][3] In our patient, hydration and careful titration of epidural local anesthetics provided excellent and safe regional block for cesarean section in the presence of moderate subaortic stenosis. Peripheral vasodilation from chemical sympathectomy can reduce venous return significantly, resulting in severe reduction in blood pressure and tissue perfusion.…”

mentioning

confidence: 99%