2002
DOI: 10.1542/peds.110.2.354
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Identifying Children With Chronic Arthritis Based on Chief Complaints: Absence of Predictive Value for Musculoskeletal Pain as an Indicator of Rheumatic Disease in Children

Abstract: Musculoskeletal pain was the most common reason for referral to our pediatric rheumatology clinic. However, isolated musculoskeletal pain, in the absence of other signs or symptoms, is almost never a presenting complaint of children with chronic forms of arthritis. Children with arthritis more commonly present with complaints of joint swelling and/or gait disturbance. Neither ANA nor rheumatoid factor evaluations were useful in evaluating children with musculoskeletal complaints.

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Cited by 106 publications
(60 citation statements)
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“…Careful performance of a competent musculoskeletal examination is vital to the diagnostic process, particularly because musculoskeletal symptoms are not always easily volunteered by children, parental observations may be nonspecific (e.g., "my child is limping"), and joint swelling and abnormal gait (such as limp) rather than reported pain are the most common presenting features of JIA (5,6).…”
Section: Introductionmentioning
confidence: 99%
“…Careful performance of a competent musculoskeletal examination is vital to the diagnostic process, particularly because musculoskeletal symptoms are not always easily volunteered by children, parental observations may be nonspecific (e.g., "my child is limping"), and joint swelling and abnormal gait (such as limp) rather than reported pain are the most common presenting features of JIA (5,6).…”
Section: Introductionmentioning
confidence: 99%
“…The pathogenesis of JIA seen in the cervical spine is similar to others joints, with synovial inflammation, hyperaemia, and pannus formation [1,13]. The indolent process of leucocyte infiltration into the synovium and proliferation of the synovial tissue lead to a subacute type of inflammation, which may justify that pain is not the most conspicuous feature of clinical presentation of JIA, that may pain be missed, particularly in oJIA [13].…”
Section: Case Seriesmentioning
confidence: 98%
“…The indolent process of leucocyte infiltration into the synovium and proliferation of the synovial tissue lead to a subacute type of inflammation, which may justify that pain is not the most conspicuous feature of clinical presentation of JIA, that may pain be missed, particularly in oJIA [13]. This may justify the frequent absence of neck pain in JIA, regardless of CSI, and its worse prognosis [3].…”
Section: Case Seriesmentioning
confidence: 99%
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“…These findings were supported by Deane et al in a series of 31 children with positive ANA (by IFA) and no initial diagnosis of autoimmune disease followed over approximately 3 years (8). Another study found that children referred because of a positive ANA (by IFA) were no more likely to be diagnosed with a chronic inflammatory disease than children who lacked this testing (9). These studies suggest that many children referred to pediatric rheumatology clinics for positive ANA will not be diagnosed with a rheumatic disease.…”
Section: Do Not Order Autoantibody Panels Unless Positive Anas and Evmentioning
confidence: 99%