Identifying a New Target for BtOBP8: Discovery of a Small Amino Ketone Molecule Containing Benzothiazole Fragments
Danxia Wu,
Li Wang,
Wei Li
et al.
Abstract:Insects rely on odorant-binding proteins
(OBPs) for chemical
perception,
making OBPs a promising target for studying attractants and repellents
of pests, such as Bemisia tabaci. However,
no reports have reported using B. tabaci OBPs (BtOBPs) as pesticide screening targets. To
fill this gap, we obtained BtOBP8 through prokaryotic
expression and purification. Then, we confirmed its identity using
western blotting and mass spectrometry. Next, we used the sitting
drop and hanging drop methods to screen its crystal… Show more
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