Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis
Lulu Tan,
Xin Li,
Hong Qin
et al.
Abstract:Ulcerative colitis (UC) is a chronic, recurrent inflammatory bowel disease. UC confronts with severe challenges including the unclear pathogenesis and lack of specific diagnostic markers, demanding for identifying predictive biomarkers for UC diagnosis and treatment. We perform immune infiltration and weighted gene co-expression network analysis on gene expression profiles of active UC, inactive UC, and normal controls to identify UC related immune cell and hub genes. Neutrophils, M1 macrophages, activated den… Show more
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