Identification of upstream immunoregulators that target protein co-expression networks significantly associated with early-stage micropapillary/solid predominant lung adenocarcinomas
Abstract:Micropapillary- and solid-predominant lung adenocarcinomas (MPA and SPA), high-risk subtypes with poor outcomes, remain their molecular profiles unclarified. This study aimed at identifying the disease-related protein networks associated with early-stage MPA and SPA. We assessed cancerous cells laser-microdissected from FFPE tissues of an MPA group (n = 3) and a SPA group (n = 5), referencing the lepidic predominant subtype group (LPA) (n = 4). We identified forty modules of protein co-expression networks by a… Show more
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