Abstract:Nicotine use is highly prevalent and brings a huge burden on individuals, society, health-care systems and economic development. The existing mechanisms underlying nicotine’ actions can’t illuminate all basic and clinical problems thoroughly. Transfer RNA-derived small RNAs (tsRNAs) is a novel class of small non-coding RNAs (sncRNAs), possessing potential regulatory functions in various diseases. However, the roles of tsRNAs in nicotine exposure have not been determined yet. In this study, firstly we establish… Show more
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