Identification of the Signature Associated With m6A RNA Methylation Regulators and m6A-Related Genes and Construction of the Risk Score for Prognostication in Early-Stage Lung Adenocarcinoma
Abstract:BackgroundN6-methyladenosine (m6A) RNA modification play critical roles in tumorigenesis because it can change gene expression and even the function in multiple levels including the regulation of degradation, subcellular localization, splicing and local conformation changes of RNA transcripts. In this study, we aim to conduct comprehensive investigation on m6A RNA methylation regulators and m6A-related genes and their association with prognosis in early-stage Lung adenocarcinoma (LUAD). MethodsThe relevant dat… Show more
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