Identification of the Metabolites of Scutebarbatine A in Rat Plasma, Bile, Urine, and
feces by Using Ultra-high-performance Liquid Chromatography Coupled with Q
Exactive Hybrid Quadrupole-orbitrap High-resolution Mass Spectrometry
Abstract:Background:
Scutebarbatine A is a new neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata, which has many pharmacological effects, such as anti-tumor, antibacterial and anti-inflammatory. However, there are no studies on the metabolism of Scutebarbatine A.
Objective:
To explore the metabolism of Scutebarbatine A in the body, the bile, plasma, urine and feces samples of rats after administration were investigated.
Methods:
The biological samples were investigated by using ultra-high-performance liq… Show more
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