Identification of the Main Degradation Products of Patulin Generated Through Heat Detoxication Treatments

Abstract

The chemical stability of patulin (PAT) was studied in model aqueous media at different temperatures and pH values in the presence and absence of sulfites. At pH 6, 50% was degraded within one hour at 100°C. At lower pH the detoxication efficiency was strongly reduced. The compound 3-keto-5-hydroxypentanal was shown to be the main degradation product of patulin. As the hemiacetal function has to be transformed into an aldehyde before retroaldolization and lactone hydrolysis, sulfites, as expected, improved detoxication, especially at high pH. At pH 7 in the presence of 50 ppm sulfite, PAT was completely degraded within 3 h at 25°C.

Aflatoxins, Ochratoxins, Trichotecenes, Patulin, Fumonisins and Beauvericin in Finished Products for Human Consumption

“…This method can be easily implementable, is high-throughput and cost-effective. It offers simultaneous UV pasteurization of juices and reduction of PAT without severe alterations in the final product [89].…”

Developments in the Monitoring of Patulin in Fruits Using Liquid Chromatography: an Overview

“…However, it is much less stable in higher pH. Collin's group has reported that 50% of patulin degrades within 1 h at 100°C in aqueous medium at pH 6 (Collin et al 2008). They have also noted that sulfites promote patulin destruction at higher pH with complete patulin degradation achieved at pH 7 within 3-h incubation at 25°C in the presence of 50 ppm SO 2 .…”

Patulin Analysis: Sample Preparation Methodologies and Chromatographic Approaches

“…Patulin is an organic compound very soluble in water and in most organic solvents. It is stable in diluted acids and resistant to temperatures at 125ºC in the 3.5 -5.5 pH range (Collin et al, 2008, as cited in Lovett & Peeler, 1973.…”