Identification of the flame retardant tetrabromobisphenol-a in the river sediment and the mussel collected in Osaka

Watanabe, Ichiro; Kashimoto, Takashi; Tatsukawa, Ryo

doi:10.1007/bf01608765

Cited by 91 publications

(37 citation statements)

References 6 publications

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“…TBBPA has been found in river sediment (Watanabe et al, 1983;Zhang et al, 2009), sewage sludge (Sellström and Jansson, 1995;Alaee et al, 2003), air samples (Sjödin et al, 2001), and wildlife (Morris et al, 2004). It was also detected in human blood, and potential sources for human exposure are indoor environment and food (Jakobsson et al, 2002;Thomsen et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Assessing developmental toxicity and estrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio)

et al. 2014

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Section: Introductionmentioning

confidence: 99%

Assessing developmental toxicity and estrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio)

et al. 2014

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“…TBBPA and TCBPA are widely used as flame retardants in numerous products. 73) Nonylphenol and octylphenol are industrial additives used in a variety of detergents and plastics. 74) 2,4-Dichlorophenol and pentachlorophenol are extensively used in the manufacture of pesticides, herbicides, and wood preservatives.…”

Section: Required Chemical Structure For Inhibition Of Pdi Activitymentioning

confidence: 99%

Biological Functions of Protein Disulfide Isomerase as a Target of Phenolic Endocrine-disrupting Chemicals

Okada

Hashimoto

Imaoka

2010

JOURNAL OF HEALTH SCIENCE

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Endocrine disrupting chemicals (EDCs) are widespread in the environment and suspected of interfering with endocrine homeostasis. Bisphenol A (BPA), 2,2-bis(4-hydroxyphenyl)propane, an EDC, has been widely used throughout the world as an industrial chemical. BPA is a developmental, neural, and reproductive toxicant that mimics estrogen and can interfere with growth and body function. In a recent study, a BPA-binding protein was isolated from P2 fractions of rat brain, and identified as protein disulfide isomerase (PDI). PDI has been studied extensively as a key enzyme involved in the formation of the correct pattern of disulfide bonds in proteins. PDI is also known to be a membrane-associated 3,3 ,5-triiodo-L-thyronine (T 3 )-binding protein. BPA inhibits the binding of T 3 to PDI and isomerase activity of PDI. PDI has four consecutive domains, a, b, b', and a', each with a thioredoxin fold. The domains a and a' have a catalytically active Cys-Gly-His-Cys motif, while b and b' have substrate-binding sites. To address the chemical structural requirements of BPA for the inhibitory effect of PDI, several BPA analogs were tested, suggesting that the phenolic structure is important for BPA to affect PDI functions. To investigate the biological effects of BPA on PDI functions, GH3 cells were used. GH3 is a rat pituitary tumor cell line and releases growth hormone (GH) via the T 3 receptor. Over-expression of PDI suppresses the T 3 -induced release of GH and when the cells were treated with BPA together with T 3 , the amount of GH released was much increased. Thus, PDI plays an important role in the hypothalamic-pituitary-thyroid axis. In this review, the possible involvement and biological significance especially in the central nervous system, of PDI as a target of phenolic environmental chemicals, are discussed.

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“…TBBPA has been found in http://dx.doi.org/10.1016/j.chemosphere.2014.12.017 0045-6535/Ó 2014 Elsevier Ltd. All rights reserved. river sediment in Japan and China (Watanabe et al, 1983;Zhang et al, 2009), sewage sludge in Sweden and Canada (Sellström and Jansson, 1995;Alaee et al, 2003), and air samples in Sweden (Sjödin et al, 2001). TCBPA has been detected in waste paper recycling plants in Japan (Fukazawa et al, 2002), drinking water in China , sediment and sludge in USA (Voordeckers et al, 2002;Chu et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China

et al. 2015

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Identification of the flame retardant tetrabromobisphenol-a in the river sediment and the mussel collected in Osaka

Cited by 91 publications

References 6 publications

Assessing developmental toxicity and estrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio)

Assessing developmental toxicity and estrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio)

Biological Functions of Protein Disulfide Isomerase as a Target of Phenolic Endocrine-disrupting Chemicals

Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China

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