1983
DOI: 10.1001/archderm.119.2.125
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Abstract: Granuloma annulare is a lymphohistiocytic process of unknown cause characterized by necrobiotic dermal papules. Acetone-fixed frozen sections of eight granuloma annulare lesions were studied for the presence of T-cell subsets, using monoclonal antibodies to T-cell surface antigens. The palisading and perivascular lymphocytic infiltrate shows that most of the mononuclear cells are reactive with LEU-1 antibody, which characterizes peripheral T cells and activated T cells. Numerous cells were reactive with LEU-3a… Show more

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Cited by 57 publications
(40 citation statements)
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“…Buechner et al [16] found numerous T-hclper cells in gran uloma annulare, which is also confirmed by our results obtained with monoclonal anti bodies OKT 11 and Leu 3a on frozen sec tions. Quismorio et al [17] and M is lira et al [18] demonstrated considerable numbers of T-cells in sarcoidosis lesions and Kveim reactions.…”
Section: Discussionsupporting
confidence: 90%
“…Buechner et al [16] found numerous T-hclper cells in gran uloma annulare, which is also confirmed by our results obtained with monoclonal anti bodies OKT 11 and Leu 3a on frozen sec tions. Quismorio et al [17] and M is lira et al [18] demonstrated considerable numbers of T-cells in sarcoidosis lesions and Kveim reactions.…”
Section: Discussionsupporting
confidence: 90%
“…[10], The detection of hybridoma binding to these cells was obtained by peroxidase-conjugated goal anti mouse IgCi utilizing a peroxidase histochemical reac tion.…”
mentioning
confidence: 99%
“…Proske U, Wozel G. Granuloma anulare giganteum et disseminatum … Akt Dermatol 2011; 37: 210 -213 nehmlich T-Helferzellen, unterstützt die Hypothese einer zellvermittelten Immunreaktion vom Spättyp auf ein unbekanntes Antigen [7]. Zur Behandlung des Granuloma anulare stehen verschiedene therapeutische Optionen mit unterschiedlichen Erfolgen zur Verfügung.…”
Section: Kasuistik 211unclassified