Identification of seizure onset zone and preictal state based on characteristics of high frequency oscillations

Detection of recurrent activation patterns across focal seizures: Application to seizure onset zone identification

“…The results on SOZ identification at different frequency bands were shown to conceal with previous works based on gammaband (Bartolomei et al, 2008;David et al, 2011) and highfrequency oscillations (Malinowska et al, 2015;Jacobs et al, 2016) in short windows after seizure onset. But more importantly, because of the largely sustained activity of SOZ channels suring seizures, our results in the studied patients revealed that low and medium frequency bands characterize SOZ channels when activation measures are averaged along the whole seizure epoch.…”

Ictal time-irreversible intracranial EEG signals as markers of the epileptogenic zone

“…One important question of immediate practical interest is the spatial relationship between the temporally asymmetric signals we found as markers of the epileptogenic zone and other signal characteristics such as ictal (Modur et al, 2011, Malinowska et al, 2015 and interictal fast oscillations (Cho et al, 2014, Kerber et al, 2014, Okanishi et al, 2014, Gliske et al, 2016 . Clarifying this relationship will be relevant for assessing how much additional information can be provided financial time series into HVG and then constructed a multilayer ("multiplex") network, in which each layer consisted of one HVG.…”

Advances of Intracranial Electroencephalography in Localizing the Epileptogenic Zone

“…Fast ripples have also been proposed to emerge from outof-phase firing within small groups of neurons, perhaps through coupling via axonal gap junctions [34]. Several studies have examined the pre-ictal and ictal changes of HFOs [4,35,36]. The rate of HFOs has been found to increase a few seconds before seizure onset [35] and its distribution remains largely confined to the same epileptogenic area during both the interictal and ictal periods, whereas spikes are more widespread during seizures than in the interictal period [35].…”