Abstract:Esophageal squamous cell carcinoma (ESCC) is one of the deadliest solid malignancies and has a poor survival rate worldwide. Suppressive tumor microenvironment is the main cause to promote tumor development, metastasis and poor survival time. Tumor-derived secretory factors could connect tumor tissues and components in the tumor microenvironment to promote tumor progression. Here, in our study, we analyzed multiple individual transcriptome databases and found a group of secretory factors derived from tumor tis… Show more
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