Identification of Salmonella enterica serovar Typhi strain from a young Brazilian patient: the relevance of automated microbiological methods for the rapid diagnosis of systemic infections

Abstract

Introduction: Latin American countries have public health problems that are aggravated by inadequate basic sanitary conditions. Inefficient vaccination coverage, as well as the fact that a significant portion of the population is exposed to contaminated water and food, can lead to an increase in the incidence of some diseases. Methodology: the work reports a case of infection by Salmonella enterica serovar Typhi (S. Typhi), whose contagion is strictly related to personal and environmental hygiene conditions. Conclusion: accurate identification and immediate detection of the etiologic agent using automated methods, such as Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) and the BACT / ALERT System® 3D, can positively contribute to the patient's prognosis and therapeutic success. Thus, principally in the Latin American, a quick and adequate treatment is of great importance, both for the patient and to minimize the spread of multidrug-resistant strains and the consequent reduction of therapeutic options.

Correspondence on " Identification of Salmonella enterica serovar Typhi "

“…We would like to share ideas on the publications regarding "Identification of Salmonella enterica serovar Typhi strain from a young Brazilian patient: the relevance of automated microbiological methods for the rapid diagnosis of systemic infections (1)." Batista-Araújo et al concluded that "accurate identification and immediate detection of the etiologic agent using automated methods... (1)" We agree that the automated tool might be helpful for diagnosis of bacterial infection.…”

Salmonella enterica serovar Typhi infection: a public health problem in Latin America and the automated microbiological methods

“…We recently received a letter to the editor (1) about our recent clinical case published in this journal (2). The public health problems faced in Brazil and other Latin American countries are recurrent and involve multiple causes.…”

“…The present study didn´t aim to describe the disease itself, a knowledge widely described in the medical literature, not even to make an overview of public health, because is not our primary activity area, we also didn´t intend to evaluate the performance of automated diagnostic, since we are facing a clinical case (2).…”