Identification of Risk Factors for the Occurrence of Cement Leakage During Percutaneous Vertebroplasty for Painful Osteoporotic or Malignant Vertebral Fracture

Tomé-Bermejo, Félix; Álvarez, Luis; Piñera, Ángel R.; Duran, Carmen; Roman, Belen Lopez-San; Vlad, Maria; Mahíllo‐Fernández, Ignacio

doi:10.1016/j.spinee.2013.07.246

Cited by 16 publications

(37 citation statements)

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“…The clinical and radiological features of the ICL and non-ICL groups are shown in Table 2. After the univariate and multivariate analysis, greater fracture severity (P = 0.016), corti- (19,27,29). In our study, greater fracture severity (P = 0.016), cortical disruption of the endplate (P < 0.0001), absence of Kummell's disease (P = 0.010), and higher CT values (P = 0.050) were independent risk factors for ICL following PVP in patients with OVCFs.…”

Section: Resultsmentioning

confidence: 48%

“…They suggested that it was due to a frequently present connection between the intervertebral disc space and the intravertebral cleft (27,29). However, Tome-Bermejo et al (19) took the opposite opinion. They concluded that the presence of the Kummell's disease was a protective factor limiting or preventing an ICL (19).…”

Section: Resultsmentioning

confidence: 99%

“…With the use of computed tomography (CT), the incidence is estimated at 63% to 87% (8,16,18). Yeom et al (18) divided CL into 3 different types in a typical way, while Tome-Bermejo et al (19) modified it into the following 4 types: through the basivertebral vein (type B), the segmental vein (type S), a cortical defect (type C), and intradiscal leakage (type D). Each type of CL is asymptomatic under most conditions.…”

Section: Radiographic Evaluation and Data Collectionmentioning

confidence: 99%

“…Pain with this leakage can reduce the quality of patients' lives (22)(23)(24)(25)(26). The risk factors for ICL are still under debate (19,(27)(28)(29). To date, there has been no effective nomogram to predict the risk of ICL.…”

Section: Radiographic Evaluation and Data Collectionmentioning

confidence: 99%

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Nomogram for Predicting Intradiscal Cement Leakage Following Percutaneous Vertebroplasty in Patients with Osteoporotic Related Vertebral Compression Fractures

Zhong

Zhu

et al. 2017

Pain Phys

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Background: Intradiscal cement leakage (ICL) is a common complication following percutaneous vertebroplasty (PVP). However, the risk factors for such a complication are under debate and there is no accurate predictive nomogram to predict ICL. Objectives: To establish an effective and novel nomogram for ICL following PVP in patients with osteoporotic-related vertebral compression fractures (OVCFs). Study Design: This was a retrospective study approved by the Institutional Review Board of our institution. Setting: This study consists of patients from a large academic center. Methods: Patients with OVCFs who underwent their first PVP in our department between January 2007 and December 2013 were included in this study. All the potential risk factors of ICL after PVP were recorded. Univariate and multivariate analyses were used to identify the independent risk factors. The nomogram was then created based on the identified independent risk factors. Results: A total of 241 patients and 330 vertebrae were included. The mean age of the patients was 73.5 (SD 7.9) years old, and the mean number of treated vertebrae was 1.4 per person. ICL was observed in 93 (28.2%) of the treated vertebrae. Greater fracture severity (P = 0.016), cortical disruption of the endplate (P < 0.0001), absence of Kummell’s disease (P = 0.010), and higher computed tomography (CT) values (P = 0.050) were the independent risk factors for ICL. Limitations: The main limitation of this study is that it is a retrospective study. Conclusion: Greater fracture severity, cortical disruption of the endplate, absence of Kummell’s disease, and higher CT values are the independent risk factors for ICL. The novel nomogram gives an accurate prediction of ICL. Key words: Osteoporotic vertebral compression fracture, percutaneous vertebroplasty, intradiscal cement leakage, risk factors, prediction, nomogram

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Section: Resultsmentioning

confidence: 48%

Section: Resultsmentioning

confidence: 99%

Section: Radiographic Evaluation and Data Collectionmentioning

confidence: 99%

Section: Radiographic Evaluation and Data Collectionmentioning

confidence: 99%

See 2 more Smart Citations

Nomogram for Predicting Intradiscal Cement Leakage Following Percutaneous Vertebroplasty in Patients with Osteoporotic Related Vertebral Compression Fractures

Zhong

Zhu

et al. 2017

Pain Phys

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“…Çimento kaçağı malign lezyonların tedavisinde korteks destriksiyonu ve yüksek kanlanma nedeniyle daha sık görülür.Malign hastalıklara bağlı gelişen fraktürlerde ise açık cerrahi ve radyoterapi tedavi seçeneği olmasına rağmen ağrı kontrolü yavaş sağlanmaktadır (15,27). Pek çok çalışma PVP nin ağrı üzerindeki etkisi konusunda hemfikirdir ve ağrı kontrolü saatler içerisinde meydana gelir (28,29).…”

Section: Gereç Ve Yöntemunclassified

Perkutan Transpedikuler Vertebroplastide Kemik Cimento Kacagi: Yirmi Hastanin Analizi

2018

GMJ

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Reduction of cement leakage by sequential PMMA application in a vertebroplasty model

et al. 2015

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The sequential cement injection is a simple approach to minimize the risk for leakage. Taking advantage of the temperature gradient between body and room temperature, it is possible to increase the cement viscosity inside the vertebra while keeping it low in the syringe. Using sequential injection of small cement volumes, further leakage paths are blocked before further injection of the low-viscosity cement.

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Identification of Risk Factors for the Occurrence of Cement Leakage During Percutaneous Vertebroplasty for Painful Osteoporotic or Malignant Vertebral Fracture

Cited by 16 publications

References 0 publications

Nomogram for Predicting Intradiscal Cement Leakage Following Percutaneous Vertebroplasty in Patients with Osteoporotic Related Vertebral Compression Fractures

Nomogram for Predicting Intradiscal Cement Leakage Following Percutaneous Vertebroplasty in Patients with Osteoporotic Related Vertebral Compression Fractures

Perkutan Transpedikuler Vertebroplastide Kemik Cimento Kacagi: Yirmi Hastanin Analizi

Reduction of cement leakage by sequential PMMA application in a vertebroplasty model

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