Identification of Quinolone-Traizole Hybrids as Potential Inhibitors Using in Silico Approach
Syeda Ejaz,
Aisha Alsfouk,
Tahira Shamim
et al.
Abstract:Alzheimer’s disease (AD) is a most common form of dementia and results in memory loss, disorientation, impaired thinking and changes in personality as well as mood. The dementia cases mostly turn into the Alzheimer’s disease (AD). Another disease, the Parkinson’s disease (PD), mainly affects dopaminergic neurons in substantia nigra. A series of previously synthesized quinolone-triazole hybrids were investigated and evaluated for their anti-acetyl cholinesterase and against monoamine oxidase reactive properties… Show more
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