Identification of pyroptosis subtypes and prognosis model of hepatocellular carcinoma based on pyroptosis‐related genes
Haisheng Xie,
Guanlin Huang,
Haoming Mai
et al.
Abstract:BackgroundHepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis. Pyroptosis, a type of programmed cell death, regulates tumor cell development. However, the role of pyroptosis‐related genes (PRGs) in HCC and their association with prognosis are unclear.MethodsWe conducted bioinformatics analysis to identify PRGs in The Cancer Genome Atlas‐Liver Hepatocellular Carcinoma (TCGA‐LIHC) patients. Consensus clustering classified patients into different subtypes. We used LASSO regression to es… Show more
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