Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties

Abstract

This study aimed to determine the phytochemical components, microbial inhibitory effectiveness and antioxidant properties of Aerva lanata plant extracts. The whole plant showed various medicinal applications in folklore and traditional medicine in various parts of the world. The organic extracts such as ethanol, ethyl acetate, chloroform, acetone, water and methanol were subjected for various phytochemical analysis and confirmed for the existence of flavonoids, glycosides, terpenoids and alkaloid containing components. Alternatively, the extracts were performed for the antibacterial activities against the microbial pathogens and antioxidant properties. Results indicated that, the solvent extracts showed prominent activity against the tested strains. The MIC concentrations of plant were detected from 5 mg/ml to 40 mg/ml. The plant extract was highly effective against E. coli and E. aerogenes and the MIC was 5 mg/ml. In addition, the extracts noted promising antioxidant activities. The antioxidant activities were dose dependent manner. In conclusion, A. lanata extracts showed that significant major phytochemicals and effective antioxidant and anti-microbial properties.

Green Synthesis of Multifaceted Silver Nanoparticles Using the Flower Extract of Aerva lanata and Evaluation of Its Biological and Environmental Applications

“…It is usually grown in tropical region and widely distributed in India, Africa and Philippines . Due to the presence of medicinally important phytochemicals such as glycosides, steroids, flavonoids and alkaloids it has been used as a fine medicine for diabetes, kidney stone, inflammation, diarrhea and many human threat diseases . Therefore, we have chosen the flower of Aerva lanata to synthesis the silver nanoparticles.…”

Optimization of Extraction of Polyphenolic Compounds from Medicinal Lungwort (Pulmonaria officinalis L.)

“…Literature related to pre -screening of antioxidant activity for isolated Pulmonaria officinalis L. extracts used in the food industry has shown a high value of antioxidant activity, which may be associated with a high content of flavonoids [22,23,29,35].…”

“…The antioxidant properties of phenolic compounds depend directly on their structure. Phenolic compounds contain at least one aromatic ring that carries one or more hydroxyl groups, and these compounds are able to destroy free radicals, while forming phenoxyl radicals [23,29,35].…”

“…The represented wildflower is a herbaceous perennial plant belonging to the Boraginaceae family, widely distributed in the Siberian Federal district. Pulmonaria officinalis L. has found traditional therapeutic use in the treatment of bronchitis, viral diseases, headache, laryngitis, kidney and respiratory diseases, as well as stomach and duodenal ulcer [20,21,22,23].…”

“…The presence of BAS in Pulmonaria officinalis L. contributes to the inhibition of active enzymes tyrosinase and acetylcholinextraza, which has been used in the treatment of Parkinson's and Alzheimer's diseases [23,24,25,26].…”