Identification of phenolic compounds by HPLC-ESI-MS/MS and antioxidant activity from Chilean propolis

Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile

“…It should be noted that Castro et al (2014) determined the anti-oxidant activity, and in this study it was found that the EEP of Buin propolis had the highest anti-oxidant effect in comparison to the other propolis studied. And so, since the anti-oxidant activity of the EEP obtained from Buin propolis was higher than it was for the Caleu propolis, this would in part justify the higher anti-inflammatory activity that we found in Buin propolis, since it is known that the inflammatory process produces free radicals (Farooqui and Farooqui, 2010).…”

“…The analysis of the chromatograms and mass specters was done using the program Data Analysis 3.2 (Bruker Daltonik GmbH, Germany). The identification of the compounds was done revising the scientific literature (Castro et al, 2014;Falcão et al, 2010;Gardana et al, 2007;Medana et al, 2008;Pellati et al, 2011;Righi et al, 2013) and the data base MassBank. The relative amount of each compound in each extract was calculated.…”

“…In Chilean propolis, only some of these properties have been evaluated, such as anti-oxidant (Astudillo et al, 2000;Castro et al, 2014;Russo et al, 2004), anti-bacterial (Saavedra et al, 2011), antifungal (Herrera et al, 2010) and anti-tumoral (Russo et al, 2004), among others. However, the anti-inflammatory activity through in vivo and in vitro methods has not been investigated.…”

International Regulations ofPropolisQuality: Required Assays do not Necessarily Reflect their Polyphenolic‐RelatedIn VitroActivities

“…Nevertheless, studying the antioxidant properties of natural polyphenols still accounts for most of the food chemistry‐oriented research on these compounds. Most reported data strongly supports the existence of dependence between the chemical structure of polyphenols and their in vitro antioxidant capacity (Pandey and Rizvi ; Castro and others ). Among these activities, the ability of polyphenols to scavenge reactive species such as free radicals, as well as, hypochlorous and nitrous acid, has been highlighted (Oldreive and others ; Kumar and Pandey ; Perez‐Cruz and others ; Vione and others ).…”

Caracterização e identificação de compostos com atividade antioxidante de própolis orgânica brasileira

“…Diversos trabalhos tem ressaltado os efeitos benéficos da própolis à saúde, dentre os quais se pode citar o uso contra infecções bacterianas (SFORCIN et al, 2000) e fúngicas (QUINTERO-MORA et al, 2008), atividade anti-inflamatória (REIS et al, 2000;BUENO-SILVA et al, 2013), atividade antioxidante (CASTRO et al, 2014;ALENCAR et al, 2007), antitumoral (VALENTE et al, 2011), entre outras, e na forma de alimento funcional (SHIRAHIGUE et al, 2007;CASTRO et al, 2014).…”