Identification of Pharmaceutically Important Constituents of Quinoa Root

Abstract

The present investigation was carried out to explore the bioactive compounds from the n-hexane fraction of methanolic extract of quinoa (Chenopodium quinoa Willd.) roots. For this purpose, C. quinoa roots were collected, shade dried, and crushed into a fine powder. The powdered material was extracted in methanol, filtered, and the filtrate was partitioned with n-hexane, followed by GC-MS analysis of the n-hexane fraction. The quantitative determination of this fraction revealed the presence of 15 phytochemical constituents of diverse nature. Among these, octadec-9-enoic acid (44.18%); n-hexadecanoic acid (18.87%); methyl (Z)-octadec-9-enoate (12.87%); methyl hexadecanoate (4.30%); 2,3-dihydroxypropyl elaidate (3.63%); phthalic acid (3.08%); methyl octadecanoate (2.27%) and 1,12-tridecadiene (2.00%) were prevailing as the most abundant to moderately occurring compounds. A thorough literature survey was carried out to collect information regarding the pharmaceutical properties of the identified compounds. It showed some of the identified compounds namely dodecanoic acid; tetradecanoic acid; 2-benzoyl-d-galactosan; n-hexadecanoic acid; methyl octadecanoate; octadec-9-enoic acid; and 2,3-dihydroxypropyl elaidate possess antifungal, antibacterial, antioxidant, antiviral, anti-inflammatory, and/or anti-cancer properties.

Phytochemical Composition and Cytotoxic Activity of Senecio asirensis Hexane Fraction Using In Vitro and In Silico Approaches

“…33 The most prevalent phytoconstituent found in ethanolic extracts of Cayratia trifolia and Moringa oleifera , according to Khan and Javaid, is nonacosane, which has potent anti-inflammatory, antioxidant, and cytotoxic effects. 34 Subsequent investigation revealed that nonacosane possessed the strongest antimicrobial potential against a variety of bacteria, such as Salmonella typhi , Escherichia coli , Enterobacter faecalis , Staphylococcus aureus , and Klebsiella pneumonia. 35,36 It also possesses great anti-diabetic potential.…”

Chenopodium quinoa Willd. and Amaranthus hybridus L.: Ancestral Andean Food Security and Modern Anticancer and Antimicrobial Activity

“…The antimicrobial activity of C. quinoa is due to several compound families, mainly phenolics. Compounds present in extracts of quinoa seeds, leaves, roots and inflorescences exhibit antimicrobial activity [97,98]. Examples of such activity are shown in Table 7 and Figure 4.…”