Identification of oral bacterial species associated with halitosis

Haraszthy, Violet I.; Zambon, Joseph J.; Sreenivasan, Prem K.; Zambon, M.; Gerber, Doralee; Rêgo, Rodrigo Otávio; Parker, Carol

doi:10.14219/jada.archive.2007.0325

Cited by 138 publications

(132 citation statements)

References 27 publications

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“…Previous studies evaluating oral bacterial production of H 2 S or VSCs reported that Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Treponema denticola, Solobacterium moorei, and Veillonella alcalescens were correlated with oral malodor (Stassinakis et al, 2002;Kazor et al, 2003;Tyrrell et al, 2003;Tanaka et al, 2004;Washio et al, 2005;Haraszthy et al, 2007;Takeshita et al, 2010). However, the findings were mostly based on tracking a few specific bacteria (Tanaka et al, 2004) or were dependent on bacterial culture (Tyrrell et al, 2003;Haraszthy et al, 2007). In addition, those studies that adopted non-culture-based methods used Sanger sequencing of a small number of 16S rRNA gene clones (Kazor et al, 2003;Washio et al, 2005;Haraszthy et al, 2007) or T-RFLP (Takeshita et al, 2010), which provided limited resolution of the complex oral microbiota.…”

Section: Discussionmentioning

confidence: 99%

“…Both links and distinctions were identified between these bacterial taxa and those oral-malodor-associated bacteria from other studies. Previous studies evaluating oral bacterial production of H 2 S or VSCs reported that Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Treponema denticola, Solobacterium moorei, and Veillonella alcalescens were correlated with oral malodor (Stassinakis et al, 2002;Kazor et al, 2003;Tyrrell et al, 2003;Tanaka et al, 2004;Washio et al, 2005;Haraszthy et al, 2007;Takeshita et al, 2010). However, the findings were mostly based on tracking a few specific bacteria (Tanaka et al, 2004) or were dependent on bacterial culture (Tyrrell et al, 2003;Haraszthy et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

“…However, the findings were mostly based on tracking a few specific bacteria (Tanaka et al, 2004) or were dependent on bacterial culture (Tyrrell et al, 2003;Haraszthy et al, 2007). In addition, those studies that adopted non-culture-based methods used Sanger sequencing of a small number of 16S rRNA gene clones (Kazor et al, 2003;Washio et al, 2005;Haraszthy et al, 2007) or T-RFLP (Takeshita et al, 2010), which provided limited resolution of the complex oral microbiota. Such differences in methodology could have contributed to the distinctions in the Phylogenetic abundance Leptotrichia rho=0.32 p.adj=0.03 Phylogenetic abundance Prevotella_tannerae rho=0.47 p.adj=0 identified oral-malodor-associated bacteria among the various studies.…”

Section: Discussionmentioning

confidence: 99%

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Microbial Basis of Oral Malodor Development in Humans

Yang

Huang

et al. 2013

J Dent Res

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To better understand the microbial basis of oral malodor development in humans, we used a cross-sectional and longitudinal study design and the pyrosequencing approach to track and compare the tongue microbiota associated with oral malodor in 29 Chinese adults who underwent a consecutive three-day evaluation for the amount of H 2 S excreted orally. Three levels of the oral malodor state (healthy, oral malodor, and severe oral malodor) were defined based on the H 2 S level. Community structure of the tongue plaques was more sensitive to changes of malodor state than to interpersonal variations or differences in sampling times. Within each individual, the structure of microbiota was relatively stable, while their variations were correlated with the change in the H 2 S level. Severe oral malodor microbiota were the most conserved in community structure, whereas the healthy ones were relatively varied. Oralmalodor-associated bacteria were identified. The relative abundance of Leptotrichia and Prevotella was positively correlated with oral malodor severity, whereas Hemophilus and Gemella exhibited a negative relationship with oral malodor severity. Our study provides one of the first landscapes of oral microbiota changes associated with oral malodor development and reveals microbes potentially useful to the evaluation and control of oral malodor.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Microbial Basis of Oral Malodor Development in Humans

Yang

Huang

et al. 2013

J Dent Res

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“…El Solobacterium moorei es un microorganismo que coloniza principalmente el dorso de la lengua y su prevalencia es muy alta en casos de halitosis, por el contrario es poco frecuente en individuos sin halitosis. Adicionalmente existen otros microorganismos relacionados con la halitosis (38). Los patógenos periodontales en la bolsa periodontal encuentran un ambiente ideal para la producción de CVS.…”

Section: Nichos Y Ambientes Anaeróbicos Especialesunclassified

Halitosis: Un asunto del odontólogo

Duque¹,

Tejada²

2016

CES odontol.

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La halitosis ha sido definida como un olor ofensivo y fétido en el aliento producido por factores como: mala higiene oral, infecciones dentales u orales y/o la ingestión de ciertos alimentos. El objetivo de esta revisión es evaluar el estado actual del diagnóstico, clasificación y tratamiento de la halitosis, y brindar estrategias y herramientas correctas para abordar una problemática que es tan común en la consulta odontológica. La prevalencia de la halitosis es alta y varía dependiendo de la población estudiada y el método de diagnostico usado (escalas subjetivas, mediciones organolépticas, halimeter, cromatografía de gas, test BANA ). Existen 3 tipos de halitosis: La halitosis genuina (fisiológica y patológica), la pseudohalitosis y la halitofobia. La etiología es multifactorial y existe un acuerdo en que principalmente ocurre por el metabolismo de las bacterias. La producción de compuestos volátiles y no volátiles es común en los humanos y está influenciada por factores genéticos, dieta, estrés, enfermedades y/o desordenes presentes en los individuos. Los dos tratamientos más utilizados y tradicionales para el control de la halitosis son el control mecánico de la lengua saburral y el uso de agentes antimicrobianos. La halitosis afecta una gran parte de la población, puede crear desventajas sociales y sicológicas, y aunque es de origen multifactorial su principal causa se encuentra en la cavidad oral, principalmente por factores como la placa bacteriana, gingivitis y periodontitis. El objetivo de este artículo es revisar las herramientas actuales para el diagnóstico y tratamiento de la halitosis.Palabras clave: Halitosis, Enfermedades periodontales, Biopelícula, Pruebas de halitosis. AbstractHalitosis has been defined as an offensive and fetid breath odor caused by factors such as poor oral hygiene, dental or mouth infections and / or ingestion of certain foods. The aim of this review is to assess the current state of diagnosis, classification and treatment of halitosis, providing the right strategies and tools to address a problem that is so common in dental practice. Halitosis prevalence is high and varies depending on the population studied and the diagnostic method used (subjective scales, organoleptic measurements, halymeter, gas chromatography, BANA test). There are 3 types of halitosis: Genuine halitosis (physiological and pathological), the pseudohalitosis and halitophobia. The etiology is multifactorial and there is an agreement about the cause primarily by bacterial metabolism. The production of volatile and nonvolatile compounds in humans is common Comparte Duque A, Tejada C. Enero -Junio 2016 -Pág 71ODONTOLOGÍA and is influenced by genetic factors, diet, stress, diseases and / or disorders present in individuals. The two most used and traditional treatments to control halitosis are the mechanical control of coated tongue and the use of antimicrobial agents. Halitosis affects a large part of the population may create social and psychological disadvantages, and although it is of multifactorial origi...

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“…Recently, a molecular approach based on 16S rRNA was been applied to investigate the diversity of both cultivable and uncultivable species in the human oral cavity [37][38][39]. Several investigators have attempted to identify the oral bacterial species associated with halitosis by PCR amplification of tongue-debris samples, and cloning and sequencing of 16S rRNA genes [40][41][42]. Although the size of the study populations was limited (11, 13, and 32, respectively) and their oral condition was not described, the data showed some similarities.…”

Section: Malodor-associated Microbiotamentioning

confidence: 99%