Identification of nuclear factor kappaB (NF-κB) binding motifs in Biomphalaria glabrata

Biomphalaria glabrata immunity: Post-genome advances

“…Based on mammalian studies, ligand binding by BgTNFRs may lead to the activation of mitogen-activated protein kinase (MAPK), NF-κB and AP1 signaling pathways ( Aggarwal et al, 2011 , Fig. 3 ); components of all these pathways have been identified in B. glabrata ( Humphries and Yoshino, 2006 ; Zhang and Coultas, 2011 ; Humphries and Harter, 2015 ; Adema et al, 2017 ).…”