Identification of novel tumor-associated antigens and evaluation of a panel of autoantibodies in detecting oral cancer
Weihong Xie,
Guiying Sun,
Junfen Xia
et al.
Abstract:Background
We aimed to identify tumor-associated antigen (TAA) biomarkers through bioinformatic analysis and experimental verification, and to evaluate a panel of autoantibodies against tumor-associated antigens (TAAbs) for the detection of oral cancer (OC).
Methods
GEO and TCGA databases were used to screen significantly up-regulated genes related to OC, and protein-protein interaction (PPI) analysis and Cystoscope software were used to identify k… Show more
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