Identification of novel tail-anchored membrane proteins integrated by the bacterial twin-arginine translocase
José Jesús Gallego-Parrilla,
Emmanuele Severi,
Govind Chandra
et al.
Abstract:The twin-arginine protein transport (Tat) system exports folded proteins across the cytoplasmic membranes of prokaryotes and the energy transducing-membranes of plant thylakoids and mitochondria. Proteins are targeted to the Tat machinery by N-terminal signal peptides with a conserved twin-arginine motif, and some substrates are exported as heterodimers where the signal peptide is present on one of the partner proteins. A subset of Tat substrates is found in the membrane. Tat-dependent membrane proteins usuall… Show more
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